Nanoengineered electrospun fibers and their biomedical applications: a review

被引:58
作者
Zhang, Xi [1 ]
Shi, Xuetao [2 ]
Gautrot, Julien E. [1 ]
Peijs, Ton [3 ]
机构
[1] Queen Mary Univ London, Sch Engn & Mat Sci, London, England
[2] Northwestern Polytech Univ, Sch Nat & Appl Sci, Dept Appl Chem, Xian, Peoples R China
[3] Univ Warwick, WMG, Coventry CV4 7AL, W Midlands, England
基金
欧盟第七框架计划;
关键词
Electrospinning; polymer fibers; nanostructured; nanoparticles; functionalization; biomedical; FIBROUS SCAFFOLDS; BLOCK-COPOLYMERS; DRUG-DELIVERY; NANOFIBERS; SURFACE; NANOCOMPOSITES; ANTIBACTERIAL; COMPOSITES; MORPHOLOGY; CHALLENGES;
D O I
10.1080/20550324.2020.1857121
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Electrospun fibers have received significant interests for various application areas such as filtration, composites and biomedical products due to their large surface area, good continuity, high porosity and many other unique properties. In bio-related applications, electrospun fibers have been used for in-situ drug delivery, tissue engineering scaffolds and wound dressing. In more recent years, there has been a drive toward novel electrospun fibers with added functionalities. Nanoengineering of electrospun fibers has introduced many of such novel properties. Through this review, researchers are provided with a state of the art overview of nanoenhanced electrospun fibers with added functionalities. Examples of some nanoengineered fibers include; surface functionalization, multi-component fibers, porous nanofibers, the creation of surface nano-topographies, and the incorporation of nanoparticles to create hierarchical fibrous structures for tailoring of physicochemical properties with a special focus on biomedical applications.
引用
收藏
页码:1 / 34
页数:34
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