Nondeletional pathways for the development of autoreactive thymocytes

被引:16
作者
Bendelac, A [1 ]
机构
[1] Univ Chicago, Comm Immunol, Chicago, IL 60637 USA
[2] Univ Chicago, Dept Pathol, Chicago, IL 60637 USA
关键词
D O I
10.1038/ni0604-557
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Conventional wisdom holds that autoreactive thymocytes always undergo negative selection. This paradigm should be reassessed in light of evidence showing that alternative T cell lineages can develop in certain autoreactive conditions.
引用
收藏
页码:557 / 558
页数:2
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