Mucosal and invasive fungal infections in HIV/AIDS

被引：0
作者：
Hage, CA [1 ]
Goldman, M [1 ]
Wheat, LJ [1 ]
机构：
[1] Indiana Univ, Vet Affairs Hosp, Indianapolis Dept, Sch Med,Histoplasmosis Reference Lab, Indianapolis, IN 46204 USA
来源：
EUROPEAN JOURNAL OF MEDICAL RESEARCH | 2002年 / 7卷 / 05期
关键词：
AIDS; fungal; Candida; histoplasmosis; cryptococcal doses; aspergillosis; antifungal;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Advances in the management of fungal infections in AIDS justify this review. First, their incidence has fallen with the introduction of potent antiretroviral therapy. Now, most cases occur in patients with advanced HIV disease who have failed multiple antiretroviral regimens, are nonadherent to therapy, or treatment naive. Immune reconstitution has reduced the incidence of these infections and permitted discontinuation of maintenance therapy. However, the immune response to antiretroviral therapy has resulted in paradoxical worsening in some cases, "so-called immune reconstitution inflammatory syndromes". Finally, new antifungal agents expand our treatment choices. This review updates management of fungal infections in AIDS.
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页码：236 / 241
页数：6
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