GENSAT BAG Cre-Recombinase Driver Lines to Study the Functional Organization of Cerebral Cortical and Basal Ganglia Circuits

被引：436

作者：

Gerfen, Charles R. ^{[1
]}

Paletzki, Ronald ^{[1
]}

Heintz, Nathaniel ^{[2
]}

机构：

[1] NIMH, Lab Syst Neurosci, Bethesda, MD 20892 USA

[2] Rockefeller Univ, Howard Hughes Med Inst, Mol Biol Lab, New York, NY 10021 USA

来源：

NEURON | 2013年 / 80卷 / 06期

关键词：

MOTOR CORTEX; CORTICOSTRIATAL NEURONS; PROJECTION NEURONS; PYRAMIDAL NEURONS; GENE-EXPRESSION; TRANSGENIC MICE; NEURAL CIRCUITS; RAT; CONNECTIVITY; PATHWAY;

D O I：

10.1016/j.neuron.2013.10.016

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Recent development of molecular genetic techniques are rapidly advancing understanding of the functional role of brain circuits in behavior. Critical to this approach is the ability to target specific neuron populations and circuits. The collection of over 250 BAC Cre-recombinase driver lines produced by the GENSAT project provides a resource for such studies. Here we provide characterization of GENSAT BAG-Cre driver lines with expression in specific neuroanatomical pathways within the cerebral cortex and basal ganglia.

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页码：1368 / 1383

页数：16

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