Clinical Spectrum of Reflux Esophagitis Among 25,536 Koreans Who Underwent a Health Check-up A Nationwide Multicenter Prospective, Endoscopy-based Study

被引：25

作者：

Shim, Ki-Nam ^{[2
]}

Hong, Su Jin ^{[11
]}

Sung, Jae Kyu ^{[12
]}

Park, Kyung Sik ^{[13
]}

Kim, Seong-Eun ^{[2
]}

Park, Hyun-Shin ^{[14
]}

Kim, Young Sun ^{[3
]}

Lim, Seon Hee ^{[3
]}

Kim, Chung Hyeon ^{[3
]}

Park, Min Jung ^{[3
]}

Kim, Jeong Yoon ^{[3
]}

Cho, Kyung Ran ^{[3
]}

Kim, Donghee ^{[3
]}

Park, Seun Ja ^{[15
]}

Jee, Sam-Ryong ^{[16
]}

Kim, Jim Il ^{[4
]}

Park, Joon Yong ^{[5
]}

Song, Geun Am ^{[17
]}

Jung, Hwoon-Yong ^{[6
]}

Lee, Yong Chan ^{[7
]}

Kim, Jae Gyu ^{[8
]}

Kim, Jae J. ^{[9
]}

Kim, Nayoung ^{[1
,10
]}

Park, Soo-Heon ^{[4
]}

Jung, Hyun Chae ^{[10
]}

Chung, In-Sik ^{[4
]}

机构：

[1] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Songnam 463707, Gyeonggi Do, South Korea

[2] Ewha Womans Univ, Sch Med, Dept Internal Med, Seoul, South Korea

[3] Seoul Natl Univ Hosp, Healthcare Syst Gangnam Ctr, Seoul 110744, South Korea

[4] Catholic Univ Korea, Dept Internal Med, Seoul, South Korea

[5] Hallym Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[6] Univ Ulsan, Coll Med, Dept Internal Med, Seoul, South Korea

[7] Yonsei Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[8] Chung Ang Univ, Coll Med, Dept Internal Med, Seoul 156756, South Korea

[9] Sungkyunkwan Univ, Sch Med, Dept Internal Med, Seoul, South Korea

[10] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul 151, South Korea

[11] Soonchunhyang Univ, Coll Med, Dept Internal Med, Puchon, South Korea

[12] Chungnam Natl Univ, Dept Internal Med, Taejon, South Korea

[13] Keimyung Univ, Dept Internal Med, Coll Med, Taegu, South Korea

[14] Inha Univ, Dept Internal Med, Inchon, South Korea

[15] Kosin Univ Gospel Hosp, Dept Internal Med, Pusan, South Korea

[16] Inje Univ, Coll Med, Dept Internal Med, Paik Hosp, Pusan, South Korea

[17] Busan Natl Univ, Coll Med, Dept Internal Med, Pusan, South Korea

来源：

JOURNAL OF CLINICAL GASTROENTEROLOGY | 2009年 / 43卷 / 07期

关键词：

reflux esophagitis; endoscopy; reflux symptom; HELICOBACTER-PYLORI INFECTION; INDEPENDENT RISK-FACTOR; GASTROESOPHAGEAL-REFLUX; EROSIVE ESOPHAGITIS; CHINESE POPULATION; BARRETTS-ESOPHAGUS; ABDOMINAL OBESITY; ELDERLY-PATIENTS; PEPTIC-ULCER; DISEASE;

D O I：

10.1097/MCG.0b013e3181855055

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background: Gastroesophageal reflux is a commonly encountered condition, but detailed data on reflux symptoms in Asian countries are lacking. Goals: To evaluate the prevalence and to document the clinical spectrum of endoscopic reflux esophagitis (RE). Study: A total 25,536 subjects underwent an upper gastrointestinal endoscopic examination as part of a health check, and completed a gastroesophageal reflux questionnaire. Endoscopic findings classified according to the Los Angeles (LA) classification and the data from gastroesophageal reflux questionnaire were analyzed. Results: On the basis of endoscopic findings, 2019 subjects (7.91%) were found to have RE: 5.87% in LA-A; 1.84% in LA-B; 0.18% in LA-C; and 0.02% in LA-D. Heartburn. acid regurgitation, chest pain, hoarseness, globus sensation. Cough, and epigastric soreness were found to be associated with RE (P < 0.05). Heartburn. acid regurgitation, and epigastric soreness were more frequent in LA-B than in LA-A (P < 0.05). Epigastric soreness was most bothersome in LA-A and LA-B, and acid regurgitation was most bothersome in LA-C and LA-D (P<0.01). Heartburn. hoarseness, and globus sensation were more frequent in men with RE, and acid regurgitation was most common in women. Conclusions: The prevalence of RE was found to be 7.91% in Korea, and the Profiles of reflux symptoms were found to depend on grade of RE and sex.

引用

页码：632 / 638

页数：7

共 60 条

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