Synthesis, Crystal Structure, and DNA-Binding Studies of a Cadmium(II) Complex With Bis(N-benzylbenzimidazol-2-ylmethyl)aniline

被引：9
作者：
Wu, Huilu [1 ]
Zhang, Yanhui [1 ]
Bai, Yuchen [1 ]
Wang, Xiaoli [1 ]
Kong, Jin [1 ]
Shi, Furong [1 ]
机构：
[1] Lanzhou Jiaotong Univ, Sch Chem & Biol Engn, Lanzhou 730070, Peoples R China
来源：
SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY | 2015年 / 45卷 / 10期
关键词：
bis(N-benzylbenzimidazol-2-ylmethyl)aniline; cadmium(II) complex; crystal structure; DNA binding property; BENZIMIDAZOLE DERIVATIVES; ANTIMICROBIAL ACTIVITY; COPPER(II) COMPLEX; ANTITUMOR; CLEAVAGE; SPECTRA; LIGANDS; MANGANESE(II); INHIBITION; ANTICANCER;
D O I：
10.1080/15533174.2013.862819
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A complex of cadmium (II) picrate (pic) with Bis(N-benzylbenzimidazol-2-ylmethyl)aniline (Bebba), with composition [Cd(Bebba)(2)] (pic)(2), was synthesized and characterized by elemental analysis, electrical conductivity and IR and UV/Vis spectral measurements. The crystal structure of the cadmium(II) complex has been determined by single-crystal X-ray diffraction. The cadmium(II) cation is bonded to two Bebba ligands through four benzimidazole nitrogen, resulting in a distorted octahedron geometry. The DNA-binding properties of the cadmium(II) complex were investigated by electronic absorption, fluorescence spectra and viscosity measurements. The experimental results suggest that the cadmium(II) complex binds to DNA in an intercalation mode.
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收藏
页码：1474 / 1480
页数：7
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