Hypolipidemic effect of an exo-biopolymer produced from submerged mycelial culture of Auricularia polytricha in rats

被引：30

作者：

Yang, BK

Ha, JY

Jeong, SC

Jeon, YJ

Ra, KS

Das, S

Yun, JW

Song, CH ^{[1
]}

机构：

[1] Taegu Univ, Dept Biotechnol, Kyungbuk 712714, South Korea

[2] Univ New S Wales, Dept Biotechnol, Sydney, NSW 2052, Australia

[3] Tech Jr Coll, Dept Food & Nutr, Daegu City 704350, South Korea

来源：

BIOTECHNOLOGY LETTERS | 2002年 / 24卷 / 16期

关键词：

Auricularia polytricha; exo-biopolymer; hypolipidemic effect; submerged mycelial culture;

D O I：

10.1023/A:1019831929570

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The hypolipidemic effect of an exo-biopolymer (EBP) produced from a submerged mycelial culture of the mushroom fungus, Auricularia polytricha, was investigated in the dietary-induced hyperlipidemic rats. In a dose-dependent study, the EBP was fed at 50-100 mg kg(-1) body weight and significantly decreased the concentrations of the plasma triacylglycerols, total cholesterol, and low-density lipoprotein (LDL) cholesterol. The plasma LDL cholesterol concentration was decreased up to 70%. Production of A. polytricha biomass and EBP were optimal at pH 4 with maximum growth at 20 degreesC and EBP production at 30 degreesC. Gel chromatography of the EBP revealed a single peak of a glycoprotein with a molecular size of 32 kDa. It contained 77.5% carbohydrate and 22.5% protein. The sugar and amino acid compositions of the EBP were analyzed.

引用

页码：1319 / 1325

页数：7

共 9 条

[1] The hypocholesterolemic effect of two edible mushrooms: Auricularia auricula (tree-ear) and Tremella fuciformis (white jelly-leaf) in hypercholesterolemic rats [J].