Visible-Light-Promoted Switchable Synthesis of C-3-Functionalized Quinoxalin-2(1H)-ones

被引：40
作者：
Aganda, Kim Christopher C. [1 ,3 ]
Hong, Boseok [2 ]
Lee, Anna [3 ]
机构：
[1] Myongji Univ, Dept Energy Sci & Technol, Yongin 17058, South Korea
[2] Myongji Univ, Dept Chem, Yongin 17058, South Korea
[3] Jeonbuk Natl Univ, Dept Chem, Jeonju 54896, South Korea
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2021年 / 363卷 / 05期
基金：
新加坡国家研究基金会;
关键词：
quinoxalin-2(1H)-ones; visible light; photo catalysis; radical reactions; selective synthesis; SINGLET OXYGEN; DECARBOXYLATIVE ACYLATION; PHOTOSENSITIZED OXIDATION; PHOTOREDOX CATALYSIS; METAL; DESIGN; FUNCTIONALIZATION; QUINOXALINONES; INHIBITORS; SULFOXIDES;
D O I：
10.1002/adsc.202001396
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A visible-light-promoted synthesis of quinoxalin-2(1H)-ones has been developed using 9-mesityl-10-methylacridinium perchlorate as an organo-photocatalyst. The atmosphere-controlled method (Ar/air) enabled the selective synthesis of hydroxyl- and acyl-containing quinoxalin-2(1H)-ones under mild reaction conditions without the use of any metal catalysts or toxic reagents. A fluorescent labelling experiment showed that hydroxyl-containing quinoxalin-2(1H)-ones may have utility in various biological applications as potent fluorophores.
引用
收藏
页码：1443 / 1448
页数：6
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