Visible-Light-Promoted Switchable Synthesis of C-3-Functionalized Quinoxalin-2(1H)-ones

被引：40

作者：

Aganda, Kim Christopher C. ^{[1
,3
]}

Hong, Boseok ^{[2
]}

Lee, Anna ^{[3
]}

机构：

[1] Myongji Univ, Dept Energy Sci & Technol, Yongin 17058, South Korea

[2] Myongji Univ, Dept Chem, Yongin 17058, South Korea

[3] Jeonbuk Natl Univ, Dept Chem, Jeonju 54896, South Korea

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2021年 / 363卷 / 05期

基金：

新加坡国家研究基金会;

关键词：

quinoxalin-2(1H)-ones; visible light; photo catalysis; radical reactions; selective synthesis; SINGLET OXYGEN; DECARBOXYLATIVE ACYLATION; PHOTOSENSITIZED OXIDATION; PHOTOREDOX CATALYSIS; METAL; DESIGN; FUNCTIONALIZATION; QUINOXALINONES; INHIBITORS; SULFOXIDES;

D O I：

10.1002/adsc.202001396

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A visible-light-promoted synthesis of quinoxalin-2(1H)-ones has been developed using 9-mesityl-10-methylacridinium perchlorate as an organo-photocatalyst. The atmosphere-controlled method (Ar/air) enabled the selective synthesis of hydroxyl- and acyl-containing quinoxalin-2(1H)-ones under mild reaction conditions without the use of any metal catalysts or toxic reagents. A fluorescent labelling experiment showed that hydroxyl-containing quinoxalin-2(1H)-ones may have utility in various biological applications as potent fluorophores.

引用

页码：1443 / 1448

页数：6

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