Synthesis of 4-alkyl-1(2H)-phthalazinones and 4-alkyl-2,3-benzoxazin-1-ones via ring cleavage of 3-substituted N-alkylated-3-hydroxyisoindolin-1-ones

被引：8

作者：

Chun, TG

Kim, KS

Lee, S

Jeong, TS

Lee, HY

Kim, YH

Lee, WS

机构：

[1] Korea Res Inst Biosci & Biotechnol, Taejon 305333, South Korea

[2] Korea Adv Inst Sci & Technol, Dept Chem, Taejon 305701, South Korea

[3] Korea Adv Inst Sci & Technol, Sch Mol Sci, Taejon 305701, South Korea

来源：

SYNTHETIC COMMUNICATIONS | 2004年 / 34卷 / 07期

关键词：

heterocycles; N-alkyl; hydrazine; phthalimide;

D O I：

10.1081/SCC-120030319

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Alkyl (Me, Et, i-Pr, t-Bu)-substituted phthalimdes 5a-d were easily transformed to 1(2H)-phthalazinones 8d-i and 2,3-benzoxazin-1-ones 9d,f,and j via a one-pot addition-decyclization-cyclocondensation process.

引用

页码：1301 / 1308

页数：8

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