Diagnosis and Management of Lymphatic Disorders in Congenital Heart Disease

被引:30
|
作者
Kelly, Benjamin [1 ,2 ]
Mohanakumar, Sheyanth [2 ,3 ]
Hjortdal, Vibeke Elisabeth [2 ,3 ]
机构
[1] Aarhus Univ Hosp, Dept Cardiothorac & Vasc Surg, Aarhus, Denmark
[2] Aarhus Univ, Dept Clin Med, Aarhus, Denmark
[3] Rigshosp, Dept Cardiothorac Surg, Copenhagen, Denmark
关键词
Lymphatic complications; Congenital heart disease; Chylothorax; Prolonged effusion; Protein-losing enteropathy; Plastic bronchitis; PROTEIN-LOSING ENTEROPATHY; THORACIC-DUCT LIGATION; PLASTIC BRONCHITIS; FONTAN OPERATION; POSTOPERATIVE CHYLOTHORAX; PERSISTENT CHYLOTHORAX; PLEURAL EFFUSIONS; SINGLE-VENTRICLE; HEPARAN-SULFATE; CHILDREN;
D O I
10.1007/s11886-020-01405-y
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of ReviewLymphatic disorders have received an increasing amount of attention over the last decade. Sparked primarily by improved imaging modalities and the dawn of lymphatic interventions, understanding, diagnostics, and treatment of lymphatic complications have undergone considerable improvements. Thus, the current review aims to summarize understanding, diagnostics, and treatment of lymphatic complications in individuals with congenital heart disease.Recent FindingsThe altered hemodynamics of individuals with congenital heart disease has been found to profoundly affect morphology and function of the lymphatic system, rendering this population especially prone to the development of lymphatic complications such as chylous and serous effusions, protein-losing enteropathy and plastic bronchitis.SummaryAlthough improved, a full understanding of the pathophysiology and targeted treatment for lymphatic complications is still wanting. Future research into pharmacological improvement of lymphatic function and continued implementation of lymphatic imaging and interventions may improve knowledge, treatment options, and outcome for affected individuals.
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页数:13
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