Highly efficient iridium-catalyzed asymmetric hydrogenation of β-acylamino nitroolefins

被引：34

作者：

Yan, Qiaozhi ^{[1
]}

Liu, Man ^{[1
]}

Kong, Duanyang ^{[1
]}

Zi, Guofu ^{[1
]}

Hou, Guohua ^{[1
]}

机构：

[1] Beijing Normal Univ, Coll Chem, Beijing 100875, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 85期

基金：

中国国家自然科学基金; 高等学校博士学科点专项科研基金;

关键词：

ENANTIOSELECTIVE HYDROGENATION; MICHAEL ADDITION; ACID; ENAMINES; LIGANDS; COMPLEX; NITRO;

D O I：

10.1039/c4cc05815a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first highly efficient Ir-catalyzed enantioselective hydrogenation of beta-acylamino nitroolefins is reported. This reaction provides straightforward access to chiral b-amino nitroalkanes in high yields and excellent enantioselectivities (up to >99.9% ee) catalyzed by an Ir-(R,R)-f-spiroPhos complex.

引用

页码：12870 / 12872

页数：3

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