Topographical Modulation of Pluripotency and Differentiation of Human Embryonic Stem Cells

被引：8
作者：
Wang, Peng-Yuan [1 ,2 ]
Khan, Shahnaz [3 ]
Tu Nguyen [3 ]
Kingshott, Peter [1 ]
Wong, Raymond Ching-Bong [3 ]
机构：
[1] Swinburne Univ Technol, Dept Chem & Biotechnol, Hawthorn, Vic 3122, Australia
[2] Taipei Med Univ, Grad Inst Nanomed & Med Engn, Coll Biomed Engn, Taipei 11031, Taiwan
[3] Univ Melbourne, Ctr Eye Res Australia & Ophthalmol, Dept Surg, Hawthorn, Vic 3004, Australia
来源：
IEEE TRANSACTIONS ON NANOTECHNOLOGY | 2018年 / 17卷 / 03期
基金：
澳大利亚研究理事会; 英国医学研究理事会;
关键词：
Biomaterials; binary colloidal crystals; topography; human embryonic stem cells; pluripotency; differentiation; NANOTOPOGRAPHIES;
D O I：
10.1109/TNANO.2017.2763604
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Surface topography can have significant impact on the cell fate decisions of stem cells. Construction of a biomaterial that can mimic the physiological microenvironment can be used to enhance the maintenance or differentiation of stem cells. Here, we manufacture two surfaces with monolayer binary colloidal crystals (BCCs) having different topographies, Si2PM and Si5PM, and examined their effect on maintenance and differentiation of human embryonic stem cells (hESCs). Our results demonstrated that BCCs can be coupled with vitronectin to maintain pluripotency of hESCs during culture, and with a gelatin coating to improve early definitive endoderm differentiation of hESCs using an embryonic body assay (i.e., FOXA2 up-regulation). BCCs can be used as novel cell culture substrates to support stem cell maintenance and differentiation.
引用
收藏
页码：381 / 384
页数：4
相关论文
共 11 条
[1]  
Chen GK, 2011, NAT METHODS, V8, P424, DOI [10.1038/NMETH.1593, 10.1038/nmeth.1593]
[2]   Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells [J].
Hung, Sandy S. C. ;
Van Bergen, Nicole J. ;
Jackson, Stacey ;
Liang, Helena ;
Mackey, David A. ;
Hernandez, Damian ;
Lim, Shiang Y. ;
Hewitt, Alex W. ;
Trounce, Ian ;
Pebay, Alice ;
Wong, Raymond C. B. .
AGING-US, 2016, 8 (05) :945-957
[3]   Repression of Global Protein Synthesis by Eif1a-Like Genes That Are Expressed Specifically in the Two-Cell Embryos and the Transient Zscan4-Positive State of Embryonic Stem Cells [J].
Hung, Sandy S. C. ;
Wong, Raymond C. B. ;
Sharov, Alexei A. ;
Nakatake, Yuhki ;
Yu, Hong ;
Ko, Minoru S. H. .
DNA RESEARCH, 2013, 20 (04) :391-401
[4]   Synthetic peptide-acrylate surfaces for long-term self-renewal and cardiomyocyte differentiation of human embryonic stem cells [J].
Melkoumian, Zara ;
Weber, Jennifer L. ;
Weber, David M. ;
Fadeev, Andrei G. ;
Zhou, Yue ;
Dolley-Sonneville, Paula ;
Yang, Jiwei ;
Qiu, Liqun ;
Priest, Catherine A. ;
Shogbon, Christopher ;
Martin, Arthur W. ;
Nelson, Jodelle ;
West, Peter ;
Beltzer, James P. ;
Pal, Santona ;
Brandenberger, Ralph .
NATURE BIOTECHNOLOGY, 2010, 28 (06) :606-U95
[5]   Late stage definitive endodermal differentiation can be defined by Daf1 expression [J].
Ogaki, Soichiro ;
Omori, Hisayoshi ;
Morooka, Mayu ;
Shiraki, Nobuaki ;
Ishida, Seiichi ;
Kume, Shoen .
BMC DEVELOPMENTAL BIOLOGY, 2016, 16
[6]   Binary colloidal crystals (BCCs) as a feeder-free system to generate human induced pluripotent stem cells (hiPSCs) [J].
Wang, Peng-Yuan ;
Hung, Sandy Shen-Chi ;
Thissen, Helmut ;
Kingshott, Peter ;
Wong, Raymond Ching-Bong .
SCIENTIFIC REPORTS, 2016, 6
[7]   Modulation of human multipotent and pluripotent stem cells using surface nanotopographies and surface-immobilised bioactive signals: A review [J].
Wang, Peng-Yuan ;
Thissen, Helmut ;
Kingshott, Peter .
ACTA BIOMATERIALIA, 2016, 45 :31-59
[8]   Self-assembled binary colloidal crystal monolayers as cell culture substrates [J].
Wang, Peng-Yuan ;
Pingle, Hitesh ;
Koegler, Peter ;
Thissen, Helmut ;
Kingshott, Peter .
JOURNAL OF MATERIALS CHEMISTRY B, 2015, 3 (12) :2545-2552
[9]   Modulation of Human Mesenchymal Stem Cell Behavior on Ordered Tantalum Nanotopographies Fabricated Using Colloidal Lithography and Glancing Angle Deposition [J].
Wang, Peng-Yuan ;
Bennetsen, Dines T. ;
Foss, Morten ;
Ameringer, Thomas ;
Thissen, Helmut ;
Kingshott, Peter .
ACS APPLIED MATERIALS & INTERFACES, 2015, 7 (08) :4979-4989
[10]   Modulation of Alignment and Differentiation of Skeletal Myoblasts by Submicron Ridges/Grooves Surface Structure [J].
Wang, Peng-Yuan ;
Yu, Hung-Te ;
Tsai, Wei-Bor .
BIOTECHNOLOGY AND BIOENGINEERING, 2010, 106 (02) :285-294
12