Injuries and outcomes associated with traumatic falls in the elderly population on oral anticoagulant therapy

被引:49
作者
Boltz, Melissa M. [1 ]
Podany, Abigail B. [1 ]
Hollenbeak, Christopher S. [1 ,2 ]
Armen, Scott B. [1 ]
机构
[1] Penn State Univ, Coll Med, Dept Surg, Hershey, PA 17033 USA
[2] Penn State Univ, Coll Med, Dept Publ Hlth Sci, Hershey, PA 17033 USA
来源
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | 2015年 / 46卷 / 09期
关键词
Elderly; Trauma; Falls; Oral anticoagulation; BRAIN-INJURY; PREINJURY WARFARIN; INTRACRANIAL HEMORRHAGE; HEAD-INJURY; MORTALITY; RISK; ANTIPLATELET; CLOPIDOGREL; INCREASE; IMPACT;
D O I
10.1016/j.injury.2015.06.013
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Introduction: Fall risk for older adults is a multi-factorial public health problem as 90% of geriatric injuries are caused by traumatic falls. The CDC estimated 33% of adults >65 years incurred a fall in 2011, with 30% resulting in moderate injury. While much has been written about overall risk to trauma patients on oral anticoagulant (OAC) therapy, less has been reported on outcomes in the elderly trauma population. We used data from the National Trauma Data Bank (NTDB) to identify the types of injury and complications incurred, length of stay, and mortality associated with OACs in elderly patients sustaining a fall. Methods: Using standard NTDB practices, data were collected on elderly patients (>= 65 years) on OACs with diagnosis of fall as the primary mechanism of injury from 2007 to 2010. Univariate analysis was used to determine patient variables influencing risk of fall on OACs. Odds ratios were calculated for types of injury sustained and post-trauma complications. Logistic regression was used to determine mortality associated with type of injury incurred. Results: Of 118,467 elderly patients sampled, OAC use was observed in 444. Predisposing risk factors for fall on OACs were >1 comorbidity (p < 0.0001). Patients on OACs were 188% and 370% more likely to develop 2 and >3 complications (p < 0.0001); the most significant being ARDS and ARF (p < 0.0001). The mortality rate on OACs was 16%. Injuries to the GI tract, liver, spleen, and kidney (p < 0.0002) were more likely to occur. However, if patients suffered a mortality, the most significant injuries were skull fractures and intracranial haemorrhage (p < 0.0001). Conclusions: Risks of anticoagulation in elderly trauma patients are complex. While OAC use is a predictor of 30-day mortality after fall, the injuries sustained are markedly different between the elderly who die and those who do not. As a result there is a greater need for healthcare providers to identify preventable and non-preventable risks factors indicative of falls in the anti-coagulated elderly patient. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1765 / 1771
页数:7
相关论文
共 19 条
[1]   High-risk geriatric protocol: Improving mortality in the elderly [J].
Bradburn, Eric ;
Rogers, Frederick B. ;
Krasne, Margaret ;
Rogers, Amelia ;
Horst, Michael A. ;
Belan, Matthew J. ;
Miller, Jo Ann .
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2012, 73 (02) :435-439
[2]   Traumatic brain injury in anticoagulated patients [J].
Cohen, DB ;
Rinker, C ;
Wilberger, JE .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2006, 60 (03) :553-557
[3]   The impact of preinjury antiplatelet and anticoagulant pharmacotherapy on outcomes in elderly patients with hemorrhagic brain injury [J].
Fortuna, Gerald R. ;
Mueller, Eric W. ;
James, Laura E. ;
Shutter, Lori A. ;
Butler, Karyn L. .
SURGERY, 2008, 144 (04) :598-605
[4]   Advanced age and preinjury warfarin anticoagulation increase the risk of mortality after head trauma [J].
Franko, Jan ;
Kish, Karen J. ;
O'Connell, Brendan G. ;
Subramanian, Sujata ;
Yuschak, James V. .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2006, 61 (01) :107-110
[5]   A comparative investigation of methods for logistic regression with separated or nearly separated data [J].
Heinze, Georg .
STATISTICS IN MEDICINE, 2006, 25 (24) :4216-4226
[6]   Preinjury Warfarin Worsens Outcome in Elderly Patients Who Fall From Standing [J].
Howard, Jerry Lee, II ;
Cipolle, Mark D. ;
Horvat, Sarah A. ;
Sabella, Victoria M. ;
Reed, James F., III ;
Fulda, Gerard ;
Tinkoff, Glen ;
Pasquale, Michael D. .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2009, 66 (06) :1518-1524
[7]   Predictors of Mortality in Trauma Patients With Intracranial Hemorrhage on Preinjury Aspirin or Clopidogrel [J].
Ivascu, Felicia A. ;
Howells, Greg A. ;
Junn, Fredrick S. ;
Bair, Holly A. ;
Bendick, Phillip J. ;
Janczyk, Randy J. .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2008, 65 (04) :785-788
[8]  
Karni A, 2001, AM SURGEON, V67, P1098
[9]   Intracranial complications of preinjury anticoagulation in trauma patients with head injury [J].
Mina, AA ;
Knipfer, JF ;
Park, DY ;
Bair, HA ;
Howells, GA ;
Bendick, PJ .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2002, 53 (04) :668-672
[10]  
National Trauma Data Bank, 2013, ANN REP 2012