Critical Enhancements of MRI Contrast and Hyperthermic Effects by Dopant-Controlled Magnetic Nanoparticles

被引:487
作者
Jang, Jung-tak [1 ]
Nah, Hyunsoo [1 ]
Lee, Jae-Hyun [1 ]
Moon, Seung Ho [1 ]
Kim, Min Gyu [1 ]
Cheon, Jinwoo [1 ]
机构
[1] Yonsei Univ, Dept Chem, Seoul 120749, South Korea
关键词
imaging agents; magnetic properties; magnetism engineering; nanostructures; zinc; ZINC FERRITE NANOPARTICLES; FEPT NANOPARTICLES; NANOCRYSTALS; SPINEL; PROBES; AGENTS; MN; CO; DIAGNOSIS; DESIGN;
D O I
10.1002/anie.200805149
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Doped up: The incorporation of Zn2+ dopants in tetrahedral sites leads to the successful magnetism tuning of spinel metal ferrite nanoparticles (see picture). (Zn0.4Mn0.6)Fe2O4 nanoparticles exhibit the highest magnetization value among the metal ferrite nanoparticles. Such high magnetism results in the largest MRI contrast effects (r2=860 mm-1 s-1) reported to date and also huge hyperthermic effects. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:1234 / 1238
页数:5
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