Critical Enhancements of MRI Contrast and Hyperthermic Effects by Dopant-Controlled Magnetic Nanoparticles

被引：473

作者：

Jang, Jung-tak ^{[1
]}

Nah, Hyunsoo ^{[1
]}

Lee, Jae-Hyun ^{[1
]}

Moon, Seung Ho ^{[1
]}

Kim, Min Gyu ^{[1
]}

Cheon, Jinwoo ^{[1
]}

机构：

[1] Yonsei Univ, Dept Chem, Seoul 120749, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 07期

关键词：

imaging agents; magnetic properties; magnetism engineering; nanostructures; zinc; ZINC FERRITE NANOPARTICLES; FEPT NANOPARTICLES; NANOCRYSTALS; SPINEL; PROBES; AGENTS; MN; CO; DIAGNOSIS; DESIGN;

D O I：

10.1002/anie.200805149

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Doped up: The incorporation of Zn2+ dopants in tetrahedral sites leads to the successful magnetism tuning of spinel metal ferrite nanoparticles (see picture). (Zn0.4Mn0.6)Fe2O4 nanoparticles exhibit the highest magnetization value among the metal ferrite nanoparticles. Such high magnetism results in the largest MRI contrast effects (r2=860 mm-1 s-1) reported to date and also huge hyperthermic effects. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1234 / 1238

页数：5

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