L-Proline catalyzed one-pot multi-component synthesis of 2-(1,3-dipheny1-1H-pyrazol-4-yl)quinazolin-4(3H)-one derivatives and their biological studies

被引：20
|
作者：
Mehta, Hemal B. [1 ]
Dixit, Bharat C. [2 ]
Dixit, Ritu B. [1 ]
机构：
[1] Ashok & Rita Patel Inst Integrated Study & Res Bi, New Vallabh Vidyanagar 388121, India
[2] Sardar Patel Univ, VP & RPTP Sci Coll, Dept Chem, Vallabh Vidyanagar 388120, Gujarat, India
来源：
CHINESE CHEMICAL LETTERS | 2014年 / 25卷 / 05期
关键词：
Quinazolin-4(3H)-one; Pyrazole; L-Proline; Antimicrobial; Antifungal; Anti-tubercular activity; AGENTS;
D O I：
10.1016/j.cclet.2014.03.015
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new series of quinazolin-4(3H)-one derivatives containing a (1,3-dipheny1-1H-pyrazol-4-y1) core with substituents at the 2-position and aromatic or heteroaromatic substituents at the 3-position were synthesized using an L-proline catalyzed one-pot multi-component reaction approach. All the synthesized compounds were characterized and screened for their antimicrobial, antifungal and anti-tubercular activities. (C) 2014 Ritu B. Dixit. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码：741 / 744
页数：4
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