Design and synthesis of novel 2-hydroxy-1,4-benzoxazine derivatives through three-component Petasis reaction catalysed by pyridinium toluene-sulphonate

被引：6

作者：

Mahdjoub, Sara ^{[1
]}

Derablia, Chamseddine ^{[1
]}

Boulcina, Raouf ^{[1
]}

Kirsch, Gilbert ^{[2
]}

Debache, Abdelmadjid ^{[1
]}

机构：

[1] Univ Constantine 1, Lab Synth Mol Interets Biol, Constantine 25000, Algeria

[2] Univ Lorraine, SRSMC Site Messin UMR 6575, F-57070 Metz, France

来源：

JOURNAL OF CHEMICAL RESEARCH | 2016年 / 08期

关键词：

multicomponent condensation; Petasis reaction; PPTS; boronic acids; secondary amines; 2-hydroxy-1,4-benzoxazines; BENZOXAZINE; AGENTS;

D O I：

10.3184/174751916X14656634976813

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A variety of novel 2-hydroxy-1,4-benzoxazines were synthesised through the Petasis multicomponent reaction of 2-[(arylmethyl)amino] phenols with arylboronic acids and glyoxal catalysed by pyridinium toluene-p-sulphonate. A plausible reaction mechanism has also been proposed.

引用

页码：449 / 452

页数：4

共 3 条

[1] A new and efficient one-pot synthesis of 2-hydroxy-1, 4-dihydrobenzoxazines via a three-component Petasis reaction
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Boulcina, Raouf
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TETRAHEDRON LETTERS, 2014, 55 (37) : 5124 - 5128
[2] Design and synthesis of novel PEG-conjugated 20(S)-camptothecin sulfonylamidine derivatives with potent in vitro antitumor activity via Cu-catalyzed three-component reaction
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Gao, Wen-Jing
Cheng, Pi-Le
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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 25 (13) : 2690 - 2693
[3] One-pot, simple, and facile synthesis of 4-(3-benzylbenzo[d]thiazol-2(3H)-ylidene)-cyclohexa-2,5-dien-1-one derivatives via a novel three-component reaction
Nassiri, Mahmoud
JOURNAL OF CHEMICAL RESEARCH, 2023, 47 (04)

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