Variations in Coronary Artery Disease Secondary Prevention Prescriptions Among Outpatient Cardiology Practices Insights From the NCDR (National Cardiovascular Data Registry)

被引:78
作者
Maddox, Thomas M. [1 ,2 ,3 ]
Chan, Paul S. [4 ,5 ]
Spertus, John A. [4 ,5 ]
Tang, Fengming [4 ]
Jones, Phil [4 ]
Ho, P. Michael [1 ,2 ,3 ]
Bradley, Steven M. [1 ,2 ,3 ]
Tsai, Thomas T. [1 ,2 ,3 ]
Bhatt, Deepak L. [6 ,7 ]
Peterson, Pamela N. [2 ,3 ,8 ]
机构
[1] Vet Affairs Eastern Colorado Hlth Care Syst, Denver, CO USA
[2] Univ Colorado, Sch Med, Denver, CO USA
[3] Colorado Cardiovasc Outcomes Res Consortium, Denver, CO USA
[4] St Lukes Hosp, Mid Amer Heart Inst, Kansas City, MO 64111 USA
[5] Univ Missouri, Kansas City, MO 64110 USA
[6] Brigham & Womens Hosp, Vet Affairs Boston Hlth Care Syst, Boston, MA 02115 USA
[7] Harvard Univ, Sch Med, Boston, MA USA
[8] Denver Hlth Med Ctr, Denver, CO USA
基金
美国国家卫生研究院; 美国医疗保健研究与质量局;
关键词
CAD; outpatient practice; secondary prevention; LOGISTIC-REGRESSION; HEART-ASSOCIATION; QUALITY; PERFORMANCE; RISK; CARE; ATHEROTHROMBOSIS; IMPROVEMENT; INFARCTION; PHYSICIAN;
D O I
10.1016/j.jacc.2013.09.053
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives This study assessed practice variations in secondary prevention medication prescriptions among coronary artery disease (CAD) patients treated in outpatient practices participating in the National Cardiovascular Data Registry (NCDR) Practice Innovation and Clinical Excellence (PINNACLE) registry. Background Among patients with CAD, secondary prevention with a combination of beta-blockers, angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, and statins reduces cardiac mortality and myocardial infarction (MI). Accordingly, every CAD patient should receive the combination of these medications for which they are eligible. However, little is known about current prescription patterns of these medications and the variation in use among outpatient cardiology clinics. Methods Using data from NCDR PINNACLE registry, a national outpatient cardiology practice registry, we assessed medication prescription patterns among eligible CAD patients, between July 2008 and December 2010. Overall rates of prescription and variation by practice were calculated, adjusting for patient characteristics. Results Among 156,145 CAD patients in 58 practices, 103,830 (66.5%) patients were prescribed the optimal combination of medications for which they were eligible. The median rate of optimal combined prescription by practice was 73.5% and varied from 28.8% to 100%. After adjustment for patient factors, the practice median rate ratio for prescription was 1.25 (95% confidence interval: 1.20 to 1.32), indicating a 25% likelihood that 2 random practices would differ in treating identical CAD patients. Conclusions Among a national registry of CAD patients treated in outpatient cardiology practices, over one-third of patients failed to receive their optimal combination of secondary prevention medications. Significant variation was observed across practices, even after adjusting for patient characteristics, suggesting that quality improvement efforts may be needed to support more uniform practice. (C) 2014 by the American College of Cardiology Foundation
引用
收藏
页码:539 / 546
页数:8
相关论文
共 19 条
[1]   Comparative Determinants of 4-Year Cardiovascular Event Rates in Stable Outpatients at Risk of or With Atherothrombosis [J].
Bhatt, Deepak L. ;
Eagle, Kim A. ;
Ohman, E. Magnus ;
Hirsch, Alan T. ;
Goto, Shinya ;
Mahoney, Elizabeth M. ;
Wilson, Peter W. F. ;
Alberts, Mark J. ;
D'Agostino, Ralph ;
Liau, Chiau-Suong ;
Mas, Jean-Louis ;
Roether, Joachim ;
Smith, Sidney C., Jr. ;
Salette, Genevieve ;
Contant, Charles F. ;
Massaro, Joseph M. ;
Steg, Ph. Gabriel .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 304 (12) :1350-1357
[2]   International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis [J].
Bhatt, DL ;
Steg, PG ;
Ohman, EM ;
Hirsch, AT ;
Ikeda, Y ;
Mas, JL ;
Goto, S ;
Liau, CS ;
Richard, AJ ;
Röther, J ;
Wilson, PWF ;
Andersen-Dalheim, H ;
Anderson, P ;
Anell, B ;
Arber, S ;
Armstrong, K ;
Arnot, D ;
Baldam, A ;
Barratt, I ;
Barresi, S ;
Beder, J ;
Benson, M ;
Bergman, F ;
Best, J ;
Bhasim, R ;
Bovell, G ;
Bowman, N ;
Brkic, M ;
Bromberger, D ;
Brown, D ;
Brown, J ;
Brownstein, M ;
Bruce, A ;
Buonopane, J ;
Burns, S ;
Butler, A ;
Byrne, D ;
Carson, J ;
Cassimatis, P ;
Chaffey, G ;
Chambers, D ;
Chan, WJ ;
Chan, B ;
Cheatham, J ;
Chen, R ;
Cheong, B ;
Cheung, C ;
Chin, J ;
Chiu, A ;
Choo, E .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2006, 295 (02) :180-189
[3]   Achieving rapid door-to-balloon times - How top hospitals improve complex clinical systems [J].
Bradley, EH ;
Curry, LA ;
Webster, TR ;
Mattera, JA ;
Roumanis, SA ;
Radford, MJ ;
McNamara, RL ;
Barton, BA ;
Berg, DN ;
Krumholz, HM .
CIRCULATION, 2006, 113 (08) :1079-1085
[4]   Practice-Level Variation in Warfarin Use Among Outpatients With Atrial Fibrillation (from the NCDR PINNACLE Program) [J].
Chan, Paul S. ;
Maddox, Thomas M. ;
Tang, Fengming ;
Spinler, Sarah ;
Spertus, John A. .
AMERICAN JOURNAL OF CARDIOLOGY, 2011, 108 (08) :1136-1140
[5]   Cardiac Performance Measure Compliance in Outpatients [J].
Chan, Paul S. ;
Oetgen, William J. ;
Buchanan, Donna ;
Mitchell, Kristi ;
Fiocchi, Fran F. ;
Tang, Fengming ;
Jones, Philip G. ;
Breeding, Tracie ;
Thrutchley, Duane ;
Rumsfeld, John S. ;
Spertus, John A. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2010, 56 (01) :8-14
[6]   The Improving Continuous Cardiac Care (IC3) Program and Outpatient Quality Improvement [J].
Chan, Paul S. ;
Oetgen, William J. ;
Spertus, John A. .
AMERICAN JOURNAL OF MEDICINE, 2010, 123 (03) :217-219
[7]   ACCF/AHA/AMA-PCPI 2011 Performance Measures for Adults With Coronary Artery Disease and Hypertension A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Performance Measures and the American Medical Association-Physician Consortium for Performance Improvement [J].
Drozda, Joseph, Jr. ;
Messer, Joseph V. ;
Spertus, John ;
Abramowitz, Bruce ;
Alexander, Karen ;
Beam, Craig T. ;
Bonow, Robert O. ;
Burkiewicz, Jill S. ;
Crouch, Michael ;
Goff, David C., Jr. ;
Hellman, Richard ;
James, Thomas, III ;
King, Marjorie L. ;
Machado, Edison A., Jr. ;
Ortiz, Eduardo ;
O'Toole, Michael ;
Persell, Stephen D. ;
Pines, Jesse M. ;
Rybicki, Frank J. ;
Sadwin, Lawrence B. ;
Sikkema, Joanna D. ;
Smith, Peter K. ;
Torcson, Patrick J. ;
Wong, John B. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2011, 58 (03) :316-336
[8]  
Goldstein H., 2002, Understanding Statistics, V1, P223, DOI 10.1207/S15328031US0104_02
[9]   Importance of therapy intensification and medication nonadherence for blood pressure control in patients with coronary disease [J].
Ho, P. Michael ;
Magid, David J. ;
Shetterly, Susan M. ;
Olson, Kari L. ;
Peterson, Pamela N. ;
Masoudi, Frederick A. ;
Rumsfeld, John S. .
ARCHIVES OF INTERNAL MEDICINE, 2008, 168 (03) :271-276
[10]   Outcome of acute myocardial, infarction according to the specialty of the admitting physician [J].
Jollis, JG ;
DeLong, ER ;
Peterson, ED ;
Muhlbaier, LH ;
Fortin, DF ;
Califf, RM ;
Mark, DB .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (25) :1880-1887