Synthesis of highly functionalized macrocycles by tandem multicomponent reactions and intramolecular Sonogashira cross-coupling

被引：10

作者：

Niu, Teng-fei ^{[1
]}

Sun, Mu ^{[1
]}

Lv, Mei-fang ^{[1
]}

Yi, Wen-bin ^{[1
]}

Cai, Chun ^{[1
]}

机构：

[1] Nanjing Univ Sci & Technol, Chem Engn Coll, Nanjing 210094, Jiangsu, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2013年 / 11卷 / 41期

关键词：

DIVERSITY-ORIENTED SYNTHESIS; ONE-POT SYNTHESIS; DRUGLIKE MACROCYCLES; MACROCYCLIZATIONS; DISCOVERY; CONSTRUCTION; ROUTE;

D O I：

10.1039/c3ob41367e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient chemoselective process for the synthesis of 14- and 15-membered triazole-containing macrocycle compounds has been developed through the combination of two multicomponent reactions and an intramolecular Sonogashira cross-coupling reaction.

引用

页码：7232 / 7238

页数：7

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