Toxoplasmosis in pregnancy

被引:37
作者
Ahmed, Maimoona [1 ]
Sood, Akanksha [2 ]
Gupta, Janesh [3 ]
机构
[1] Aldara Hosp & Med Ctr, Womens Hlth Dept, Riyadh, Saudi Arabia
[2] Manchester Univ Hosp NHS Fdn Trust, St Marys Hosp, Manchester, Lancs, England
[3] Univ Birmingham, Birmingham Womens & Childrens NHS Fdn Trust, Inst Metab & Syst Res IMSR, Birmingham, W Midlands, England
关键词
Toxoplasmosis; Mother-to-child transmission; Congenital toxoplasmosis; CENTRAL-NERVOUS-SYSTEM; TO-CHILD TRANSMISSION; CONGENITAL TOXOPLASMOSIS; GONDII INFECTION; DIAGNOSIS; RISK; WOMEN; BIRTH;
D O I
10.1016/j.ejogrb.2020.10.003
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Toxoplasmosis is one of the common chronic infections caused by the parasite Toxoplasma gondii. Even though its infection in healthy non-pregnant women is self-limited and largely asymptomatic, the main concern is the risk to the fetus by vertical transmission in pregnancy. Congenital toxoplasmosis can result in permanent neurological damage and even serious morbidity such as blindness. Screening programs are implemented in various countries depending on the prevalence and virulence of the parasite in the respective regions. Upon diagnosis of infection, appropriate antibiotic therapy should be initiated as it has been proven to reduce the risk of fetal transmission. Primary prevention remains the key intervention to avoid the infection and hence patient education is an important aspect of the management. (C) 2020 Elsevier B.V. All rights reserved.
引用
收藏
页码:44 / 50
页数:7
相关论文
共 44 条
[31]   Toxoplasmosis in Pregnancy: Prevention, Screening, and Treatment [J].
Paquet, Caroline ;
Yudin, Mark H. ;
Allen, Victoria M. ;
Bouchard, Celine ;
Boucher, Marc ;
Caddy, Sheila ;
Castillo, Eliana ;
Money, Deborah M. ;
Murphy, Kellie E. ;
Ogilvie, Gina ;
van Schalkwyk, Julie ;
Senikas, Vyta .
JOURNAL OF OBSTETRICS AND GYNAECOLOGY CANADA, 2013, 35 (01) :78-79
[32]  
Peyron F., 2016, Infectious Diseases of the Fetus and Newborn Infant, V8th, P949
[33]  
Picone O, J GYNECOL OBSTET HUM
[34]   TOXOPLASMOSIS OF THE CENTRAL-NERVOUS-SYSTEM IN THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME [J].
PORTER, SB ;
SANDE, MA .
NEW ENGLAND JOURNAL OF MEDICINE, 1992, 327 (23) :1643-1648
[35]   In Utero and at Birth Diagnosis of Congenital Toxoplasmosis Use of Likelihood Ratios for Clinical Management [J].
Rabilloud, Muriel ;
Wallon, Martine ;
Peyron, Francois .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2010, 29 (05) :421-425
[36]  
Remington J.S., 2006, Infectious Diseases of the Fetus and Newborn Infant, P947, DOI DOI 10.1016/B0-72-160537-0/50033-5
[37]  
REMINGTON JS, 1994, INFECT DIS FETUS NEW, P140
[38]   Is Toxoplasma gondii type related to clinical outcome in human congenital infection? Systematic and critical review [J].
Rico-Torres, C. P. ;
Vargas-Villavicencio, J. A. ;
Correa, D. .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2016, 35 (07) :1079-1088
[39]   Prenatal diagnosis using polymerase chain reaction on amniotic fluid for congenital toxoplasmosis [J].
Romand, S ;
Wallon, M ;
Franck, J ;
Thulliez, P ;
Peyron, F ;
Dumon, H .
OBSTETRICS AND GYNECOLOGY, 2001, 97 (02) :296-300
[40]  
SEVER JL, 1988, PEDIATRICS, V82, P181