Toxoplasmosis in pregnancy

被引:37
作者
Ahmed, Maimoona [1 ]
Sood, Akanksha [2 ]
Gupta, Janesh [3 ]
机构
[1] Aldara Hosp & Med Ctr, Womens Hlth Dept, Riyadh, Saudi Arabia
[2] Manchester Univ Hosp NHS Fdn Trust, St Marys Hosp, Manchester, Lancs, England
[3] Univ Birmingham, Birmingham Womens & Childrens NHS Fdn Trust, Inst Metab & Syst Res IMSR, Birmingham, W Midlands, England
关键词
Toxoplasmosis; Mother-to-child transmission; Congenital toxoplasmosis; CENTRAL-NERVOUS-SYSTEM; TO-CHILD TRANSMISSION; CONGENITAL TOXOPLASMOSIS; GONDII INFECTION; DIAGNOSIS; RISK; WOMEN; BIRTH;
D O I
10.1016/j.ejogrb.2020.10.003
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Toxoplasmosis is one of the common chronic infections caused by the parasite Toxoplasma gondii. Even though its infection in healthy non-pregnant women is self-limited and largely asymptomatic, the main concern is the risk to the fetus by vertical transmission in pregnancy. Congenital toxoplasmosis can result in permanent neurological damage and even serious morbidity such as blindness. Screening programs are implemented in various countries depending on the prevalence and virulence of the parasite in the respective regions. Upon diagnosis of infection, appropriate antibiotic therapy should be initiated as it has been proven to reduce the risk of fetal transmission. Primary prevention remains the key intervention to avoid the infection and hence patient education is an important aspect of the management. (C) 2020 Elsevier B.V. All rights reserved.
引用
收藏
页码:44 / 50
页数:7
相关论文
共 44 条
[21]   Congenital toxoplasmosis in the United Kingdom: to screen or not to screen? [J].
Gilbert, RE ;
Peckham, CS .
JOURNAL OF MEDICAL SCREENING, 2002, 9 (03) :135-141
[22]   NEONATAL SEROLOGIC SCREENING AND EARLY TREATMENT FOR CONGENITAL TOXOPLASMA-GONDII INFECTION [J].
GUERINA, NG ;
HSU, HW ;
MEISSNER, HC ;
MAGUIRE, JH ;
LYNFIELD, R ;
STECHENBERG, B ;
ABROMS, I ;
PASTERNACK, MS ;
HOFF, R ;
EATON, RB ;
GRADY, GF ;
CHEESEMAN, SH ;
MCINTOSH, K ;
MEDEARIS, DN ;
ROBB, R ;
WEIBLEN, BJ .
NEW ENGLAND JOURNAL OF MEDICINE, 1994, 330 (26) :1858-1863
[23]   FETAL TOXOPLASMOSIS - ULTRASONOGRAPHIC SIGNS [J].
HOHLFELD, P ;
MACALEESE, J ;
CAPELLAPAVLOVSKI, M ;
GIOVANGRANDI, Y ;
THULLIEZ, P ;
FORESTIER, F ;
DAFFOS, F .
ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 1991, 1 (04) :241-244
[24]   Toxoplasma gondii infection in the United States:: Seroprevalence and risk factors [J].
Jones, JL ;
Kruszon-Moran, D ;
Wilson, M ;
McQuillan, G ;
Navin, T ;
McAuley, JB .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2001, 154 (04) :357-365
[25]  
Jose Montoya, 2008, CLIN PRACT, P47
[26]   Delayed maturation of immunoglobulin G avidity: implication for the diagnosis of toxoplasmosis in pregnant women [J].
Lefevre-Pettazzoni, M. ;
Le Cam, S. ;
Wallon, M. ;
Peyron, F. .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2006, 25 (11) :687-693
[27]   Outcome of treatment for congenital toxoplasmosis, 1981-2004: The national collaborative Chicago-based, congenital toxoplasmosis study [J].
McLeod, R ;
Boyer, K ;
Karrison, T ;
Kasza, K ;
Swisher, C ;
Roizen, N ;
Jalbrzikowski, J ;
Remington, J ;
Heydemann, P ;
Noble, AG ;
Mets, M ;
Holfels, E ;
Withers, S ;
Latkany, P ;
Meier, P .
CLINICAL INFECTIOUS DISEASES, 2006, 42 (10) :1383-1394
[28]   Vertical transmission of toxoplasma by human immunodeficiency virus-infected women [J].
Minkoff, H ;
Remington, JS ;
Holman, S ;
Ramirez, R ;
Goodwin, S ;
Landesman, S .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1997, 176 (03) :555-559
[29]   Toxoplasmosis [J].
Montoya, JG ;
Liesenfeld, O .
LANCET, 2004, 363 (9425) :1965-1976
[30]   Laboratory diagnosis of Toxoplasma gondii infection and toxoplasmosis [J].
Montoya, JG .
JOURNAL OF INFECTIOUS DISEASES, 2002, 185 :S73-S82