Marginal means/rates models for multiple type recurrent event data

被引:91
作者
Cai, JW [1 ]
Schaubel, DE
机构
[1] Univ N Carolina, Dept Biostat, Chapel Hill, NC 27599 USA
[2] Univ Michigan, Dept Biostat, Ann Arbor, MI 48104 USA
关键词
marginal means/rates model; multiple type recurrent events; multi-variate survival analysis; semi-parametric model;
D O I
10.1023/B:LIDA.0000030199.23383.45
中图分类号
O1 [数学];
学科分类号
0701 ; 070101 ;
摘要
Recurrent events are frequently observed in biomedical studies, and often more than one type of event is of interest. Follow-up time may be censored due to loss to follow-up or administrative censoring. We propose a class of semi-parametric marginal means/rates models, with a general relative risk form, for assessing the effect of covariates on the censored event processes of interest. We formulate estimating equations for the model parameters, and examine asymptotic properties of the parameter estimators. Finite sample properties of the regression coefficients are examined through simulations. The proposed methods are applied to a retrospective cohort study of risk factors for preschool asthma.
引用
收藏
页码:121 / 138
页数:18
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