Gender variations in neonatal and early infant mortality in India and Pakistan: a secondary analysis from the Global Network Maternal Newborn Health Registry

被引：32

作者：

Aghai, Zubair H. ^{[1
]}

Goudar, Shivaprasad S. ^{[2
]}

Patel, Archana ^{[3
]}

Saleem, Sarah ^{[4
]}

Dhaded, Sangappa M. ^{[2
]}

Kavi, Avinash ^{[2
]}

Lalakia, Parth ^{[1
]}

Naqvi, Farnaz ^{[4
]}

Hibberd, Patricia L. ^{[5
]}

McClure, Elizabeth M. ^{[6
]}

Nolen, Tracy L. ^{[6
]}

Iyer, Pooja ^{[6
]}

Goldenberg, Robert L. ^{[7
]}

Derman, Richard J. ^{[1
]}

机构：

[1] Thomas Jefferson Univ, Philadelphia, PA 19107 USA

[2] KLE Acad Higher Educ & Res JN Med Coll, Womens & Childrens Hlth Res Unit, Belagavi 590010, Karnataka, India

[3] Lata Med Res Fdn, Nagpur, Maharashtra, India

[4] Aga Khan Univ, Karachi, Pakistan

[5] Boston Univ, Sch Publ Hlth, Boston, MA USA

[6] RTI Int, Durham, NC USA

[7] Columbia Univ, Dept Obstet & Gynecol, Sch Med, New York, NY USA

来源：

REPRODUCTIVE HEALTH | 2020年 / 17卷 / Suppl 3期

关键词：

Early neonatal mortality; Late neonatal mortality; Stillbirth; Low-middle income countries; Sex variation in mortality; Global network; RISK-FACTORS; RESPIRATORY MORBIDITY; SEX-DIFFERENCES; CARE-SEEKING; RURAL INDIA; FETAL SEX; BIRTH; OUTCOMES; PRETERM; PREGNANCY;

D O I：

10.1186/s12978-020-01028-0

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

BackgroundTo determine the gender differences in neonatal mortality, stillbirths, and perinatal mortality in south Asia using the Global Network data from the Maternal Newborn Health Registry.MethodsThis study is a secondary analysis of prospectively collected data from the three south Asian sites of the Global Network. The maternal and neonatal demographic, clinical characteristics, rates of stillbirths, early neonatal mortality (1-7 days), late neonatal mortality (8-28 days), mortality between 29-42 days and the number of infants hospitalized after birth were compared between the male and female infants.ResultsBetween 2010 and 2018, 297,509 births [154,790 males (52.03%) and 142,719 females (47.97%)] from two Indian sites and one Pakistani site were included in the analysis [288,859 live births (97.1%) and 8,648 stillbirths (2.9%)]. The neonatal mortality rate was significantly higher in male infants (33.2/1,000 live births) compared to their female counterparts (27.4/1,000, p<0.001). The rates of stillbirths (31.0 vs. 26.9/1000 births) and early neonatal mortality (27.1 vs 21.6/1000 live births) were also higher in males. However, there were no significant differences in late neonatal mortality (6.3 vs. 5.9/1000 live births) and mortality between 29-42 days (2.1 vs. 1.9/1000 live births) between the two groups. More male infants were hospitalized within 42 days after birth (1.8/1000 vs. 1.3/1000 live births, p<0.001) than females.ConclusionThe risks of stillbirths, and early neonatal mortality were higher among male infants than their female counterparts. However, there was no gender difference in mortality after 7 days of age. Our results highlight the importance of stratifying neonatal mortality into early and late neonatal period to better understand the impact of gender on neonatal mortality. The information from this study will help in developing strategies and identifying measures that can reduce differences in sex-specific mortality.

引用

页数：11

共 32 条

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