Efficient microwave-assisted synthesis of new sulfonylbenzimidazole-4,7-diones: heterocyclic quinones with potential antitumor activity

被引：50
作者：
Boufatah, N [1 ]
Gellis, A [1 ]
Maldonado, J [1 ]
Vanelle, P [1 ]
机构：
[1] Univ Mediterranee, Fac Pharm, Lab Chim Organ Pharmaceut, CNRS,UM R6517,LCOP, F-13385 Marseille 5, France
来源：
TETRAHEDRON | 2004年 / 60卷 / 41期
关键词：
benzimidazole-4,7-diones; microwave irradiation; S-alkylation; sulfones;
D O I：
10.1016/j.tet.2004.07.070
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New benzimidazoloquinones substituted at 2-position by a sulfonyl group have been synthesized via a final microwave assisted step using 2-chloromethyl-1,5,6-trimethylbenzimidazole-4,7-dione 7 as starting material. (C) 2004 Elsevier Ltd. All rights reserved.
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收藏
页码：9131 / 9137
页数：7
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