Burden of Keloid Disease: A Cross-sectional Health-related Quality of Life Assessment

被引:115
作者
Bijlard, Eveline [1 ]
Kouwenberg, Casimir A. E. [1 ,2 ]
Timman, Reinier
Hovius, Steven E. R. [1 ]
Busschbach, Jan J. V. [2 ]
Mureau, Marc A. M. [1 ]
机构
[1] Univ Med Ctr Rotterdam, Dept Plast & Reconstruct & Hand Surg, Rotterdam, Netherlands
[2] Univ Med Ctr Rotterdam, Dept Psychiat, Sect Med Psychol & Psychotherapy, Erasmus MC, Rotterdam, Netherlands
关键词
keloid; health-related quality of life; POSAS; Skin-dex-29; SF-36; EQ-5D; HYPERTROPHIC SCARS; SKIN; PATHOPHYSIOLOGY; INSTRUMENT; MANAGEMENT; PRURITUS; VERSION; SCORES; SCALE;
D O I
10.2340/00015555-2498
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Keloid scars may be painful, itch severely and be cosmetically disturbing. The burden of keloid disease, how-ever, has not yet been determined. This study evaluated the association of keloid disease with health-related quality of life (HRQL) and identified indicators of burden using a cross-sectional survey study, with one disease-specific HRQL measure (Skindex-29) and 2 generic HRQL measures (SF-36 and EQ-5D-5L). A total of 106 keloid patients with no other skin diseases participated in the study. Having keloid disease was associated with a considerable impairment of emotional wellbeing, with most impairment on the emotional and mental HRQL. Pain and itch were the strongest indicators of HRQL impairment in keloid patients. Having painful or itchy keloids was related to low mental and emotional HRQL, implying that patients with keloids require access to effective treatment aimed at alleviating physical symptoms.
引用
收藏
页码:225 / 229
页数:5
相关论文
共 24 条
[1]   Translation, validation, and norming of the Dutch language version of the SF-36 Health Survey in community and chronic disease populations [J].
Aaronson, NK ;
Muller, M ;
Cohen, PDA ;
Essink-Bot, ML ;
Fekkes, M ;
Sanderman, R ;
Sprangers, MAG ;
Velde, AT ;
Verrips, E .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 1998, 51 (11) :1055-1068
[2]   DLQI scores in patients with keloids and hypertrophic scars: a prospective case control study [J].
Balci, Didem Didar ;
Inandi, Tacettin ;
Dogramaci, Cigdem Asena ;
Celik, Ebru .
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2009, 7 (08) :688-691
[3]   Quality of life of patients with keloid and hypertrophic scarring [J].
Bock, O ;
Schmid-Ott, G ;
Malewski, P ;
Mrowietz, U .
ARCHIVES OF DERMATOLOGICAL RESEARCH, 2006, 297 (10) :433-438
[4]   Critical review of generic and dermatology-specific health-related quality of life instruments [J].
Both, Hilde ;
Essink-Bot, Marie-Louise ;
Busschbach, Jan ;
Nijsten, Tamar .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2007, 127 (12) :2726-2739
[5]   The hidden cost of skin scars: quality of life after skin scarring [J].
Brown, B. C. ;
McKenna, S. P. ;
Siddhi, K. ;
McGrouther, D. A. ;
Bayat, A. .
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, 2008, 61 (09) :1049-1058
[6]   Improved discriminative and evaluative capability of a refined version of Skindex, a quality-of-life instrument for patients with skin diseases [J].
Chren, MM ;
Lasek, RJ ;
Flocke, SA ;
Zyzanski, SJ .
ARCHIVES OF DERMATOLOGY, 1997, 133 (11) :1433-1440
[7]   A POWER PRIMER [J].
COHEN, J .
PSYCHOLOGICAL BULLETIN, 1992, 112 (01) :155-159
[8]   The patient and observer scar assessment scale: A reliable and feasible tool for scar evaluation [J].
Draaijers, LJ ;
Tempelman, FRH ;
Botman, YAM ;
Tuinebreijer, WE ;
Middelkoop, E ;
Kreis, RW ;
van Zuijlen, PPM .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2004, 113 (07) :1960-1965
[9]   WHAT FACTORS AFFECT THE QUALITY OF LIFE OF PATIENTS WITH KELOIDS? [J].
Furtado, Fabianne ;
Hochman, Bernardo ;
Ferrara, Soraia Francisco ;
Dini, Gal Moreira ;
Camelo-Nunes, Jose Mario ;
Juliano, Yara ;
Ferreira, Lydia Masako .
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2009, 55 (06) :700-704
[10]  
Goldstein BG, 2014, UPTODATE