Acquired Von Willebrand Syndrome Secondary to Mitral and Aortic Regurgitation

被引：11

作者：

Wan, Siu-Hin ^{[1
]}

Liang, Jackson J. ^{[1
]}

Vaidya, Rakhee ^{[2
]}

Blackshear, Joseph L. ^{[3
]}

Chen, Dong ^{[4
]}

机构：

[1] Mayo Clin, Dept Internal Med, Rochester, MN 55905 USA

[2] Mayo Clin, Div Hematol, Rochester, MN 55905 USA

[3] Mayo Clin, Div Cardiovasc Dis, Rochester, MN 55905 USA

[4] Mayo Clin, Div Hematopathol, Rochester, MN 55905 USA

来源：

CANADIAN JOURNAL OF CARDIOLOGY | 2014年 / 30卷 / 09期

关键词：

D O I：

10.1016/j.cjca.2014.02.010

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The association between aortic stenosis and gastrointenstinal bleeding due to acquired von Willebrand syndrome (AVWS) has been well established. We report a patient with AVWS from underlying severe endocarditis-associated aortic regurgitation and pre-existing mitral regurgitation. Cardiovascular disease-related AVWS occurs from a selective loss of the largest multimers of von Willebrand factor from high shear forces, and desmopressin leads to transient clinical improvement.

引用

页码：1108.e9 / 1108.e10

页数：2

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