Upregulation of endogenous thrombopoietin receptor (MPL) with in vivo passage of calreticulin (CALR) mutant Ba/F3 cells, highlighting MPL as the requisite cytokine receptor for CALR mediated transformation

被引:0
|
作者
Brooks, Stefan A. [1 ]
Kim, Daniel M. [2 ]
Morse, Sarah J. [2 ]
Nguyen, Quy H. [1 ]
Craver, Brianna M. [1 ]
Lai, Hew Yeng [1 ]
Fleischman, Angela G. [1 ,2 ]
机构
[1] Univ Calif Irvine, Dept Biol Chem, Irvine, CA 92717 USA
[2] Univ Calif Irvine, Dept Med, Div Hematol Oncol, Irvine, CA 92717 USA
关键词
Myeloproliferative neoplasm; Calreticulin; Thrombopoietin; Receptor; JAK/STAT signaling; TYROSINE KINASE JAK2; ACTIVATING MUTATION; LINE;
D O I
10.1016/j.leukres.2019.05.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:11 / 14
页数:4
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