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GABAergic synapses: their plasticity and role in sensory cortex
被引:54
作者:
Griffen, Trevor C.
[1
,2
,3
]
Maffei, Arianna
[1
,4
]
机构:
[1] SUNY Eye Res Consortium, Buffalo, NY USA
[2] SUNY Stony Brook, Program Neurosci, Stony Brook, NY 11794 USA
[3] SUNY Stony Brook, Med Scientist Training Program, Stony Brook, NY 11794 USA
[4] SUNY Stony Brook, Dept Neurobiol & Behav, Stony Brook, NY 11794 USA
来源:
FRONTIERS IN CELLULAR NEUROSCIENCE
|
2014年
/
8卷
关键词:
synaptic plasticity;
GABA;
inhibitory neurons;
sensory cortex;
inhibition;
PRIMARY VISUAL-CORTEX;
OCULAR DOMINANCE PLASTICITY;
RECEPTIVE-FIELD PROPERTIES;
CRITICAL-PERIOD PLASTICITY;
PARVALBUMIN-EXPRESSING INTERNEURONS;
RAT SOMATOSENSORY CORTEX;
PRIMARY AUDITORY-CORTEX;
WHISKER MAP PLASTICITY;
THALAMOCORTICAL RESPONSE TRANSFORMATION;
VASOACTIVE INTESTINAL POLYPEPTIDE;
D O I:
10.3389/fncel.2014.00091
中图分类号:
Q189 [神经科学];
学科分类号:
071006 ;
摘要:
The mammalian neocortex is composed of a variety of cell types organized in a highly interconnected circuit. GABAergic neurons account for only about 20% of cortical neurons. However, they show widespread connectivity and a high degree of diversity in morphology, location, electrophysiological properties and gene expression. In addition, distinct populations of inhibitory neurons have different sensory response properties, capacities for plasticity and sensitivities to changes in sensory experience. In this review we summarize experimental evidence regarding the properties of GABAergic neurons in primary sensory cortex. We will discuss how distinct GABAergic neurons and different forms of GABAergic inhibitory plasticity may contribute to shaping sensory cortical circuit activity and function.
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页数:22
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