Recent contributions to the Diversity-Oriented Synthesis (DOS) mediated by iminium ions through multicomponent Mannich-type reactions

被引:5
作者
Abonia, Rodrigo [1 ]
Castillo, Juan C. [1 ,2 ]
机构
[1] Univ Valle, Dept Chem, Cali 25360, Colombia
[2] Univ Boyaca, Dept Quim & Bioquim, Grp Invest Nucleo, Carrera 2a Este 64-169, Tunja, Colombia
关键词
Formaldehyde; multicomponent reactions; Mannich-type reactions; Diversity Oriented Synthesis; nitrogen-containing derivatives; combinatorial synthesis; BENZOTRIAZOLE METHODOLOGY; ORGANIC-SYNTHESIS; ASYMMETRIC-SYNTHESIS; EFFICIENT SYNTHESIS; ANTIFUNGAL AGENTS; ACID-DERIVATIVES; ALPHA-AMINO; INHIBITORS; DESIGN; SERIES;
D O I
10.24820/ark.5550190.p010.284
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
This short account summarizes the most recent contributions of the author and his collaborators to the Diversity Oriented Synthesis (DOS) mediated, at least in a step of the process, by Mannich-type reactions (MTR) and using formaldehyde as common starting material in all cases. Through this strategy, diverse nitrogen-containing acyclic and heterocyclic systems were synthesized, whether in straightforward or multicomponent approaches.
引用
收藏
页码:170 / 191
页数:22
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