Pseudomelanosis of the bladder - A case report

Background Pseudomelanosis is due to deposition of pseudomelanin and is best known as the entity pseudomelanosis coli. However, pseudomelanosis in. the urinary tract has never been described. Pigmentation of the urothelium, known as melanosis vesica, is characterized by deposition of melanin piginent graules without signs of atypia. Simple (true) melanosis of the bladder is uncommon. Case A 52-year-old man presented with macroscopic hematuria. Cytoscopy and microscopic evaluation revealed pigmentation of the bladder urothelium diagnosed as pseudomelanosis vesica due to deposits of melaninlike pigment in the absence of detectable melanocytes and detectable by urine cytology. Conclusion Pseudomelanosis vesica is a benign lesion that has never before been observed in the urinary tract.