Mechanisms of extracellular signal-regulated kinase (ERK) 1/2 phosphorylation following activation of relaxin family peptide receptor 3 (RXFP3) by human relaxin-3 (H3 relaxin).

被引:0
|
作者
van der Westhuizen, Emma T. [1 ]
Sexton, Patrick M. [1 ]
Summers, Roger J. [1 ]
机构
[1] Monash Univ, Dept Pharmacol, Monash, Vic 3800, Australia
来源
关键词
relaxin-3; G - protein coupled receptor; signal transduction;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:392 / 393
页数:2
相关论文
共 50 条
  • [11] Relaxin-3 receptor (RXFP3) mediated modulation of central respiratory activity
    Furuya, Werner
    Dhingra, Rishi
    Gundlach, Andrew
    Hossain, Mohammed
    Dutschmann, Mathias
    FASEB JOURNAL, 2020, 34
  • [12] Signalling profiles of H3 relaxin, H2 relaxin and R3(B.23-27) R/I5 acting at the relaxin family peptide receptor 3 (RXFP3)
    Kocan, M.
    Sarwar, M.
    Hossain, M. A.
    Wade, J. D.
    Summers, R. J.
    BRITISH JOURNAL OF PHARMACOLOGY, 2014, 171 (11) : 2827 - 2841
  • [13] A negatively charged transmembrane aspartate residue controls activation of the relaxin-3 receptor RXFP3
    Liu, Yu
    Zhang, Lei
    Shao, Xiao-Xia
    Hu, Meng-Jun
    Liu, Ya-Li
    Xu, Zeng-Guang
    Guo, Zhan-Yun
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2016, 604 : 113 - 120
  • [14] Central relaxin-3 receptor (RXFP3) activation increases ERK phosphorylation in septal cholinergic neurons and impairs spatial working memory
    Albert-Gasco, Hector
    Garcia-Aviles, Alvaro
    Moustafa, Salma
    Sanchez-Sarasua, Sandra
    Gundlach, Andrew L.
    Olucha-Bordonau, Francisco E.
    Sanchez-Perez, Ana M.
    BRAIN STRUCTURE & FUNCTION, 2017, 222 (01): : 449 - 463
  • [15] Central relaxin-3 receptor (RXFP3) activation increases ERK phosphorylation in septal cholinergic neurons and impairs spatial working memory
    Héctor Albert-Gascó
    Álvaro García-Avilés
    Salma Moustafa
    Sandra Sánchez-Sarasua
    Andrew L. Gundlach
    Francisco E. Olucha-Bordonau
    Ana M. Sánchez-Pérez
    Brain Structure and Function, 2017, 222 : 449 - 463
  • [16] Design, Synthesis, and Characterization of a Single-Chain Peptide Antagonist for the Relaxin-3 Receptor RXFP3
    Haugaard-Kedstrom, Linda M.
    Shabanpoor, Fazel
    Hossain, Mohammed Akhter
    Clark, Richard J.
    Ryan, Philip J.
    Craik, David J.
    Gundlach, Andrew L.
    Wade, John D.
    Bathgate, Ross A. D.
    Rosengren, K. Johan
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (13) : 4965 - 4974
  • [17] Binding conformation and determinants of a single-chain peptide antagonist at the relaxin-3 receptor RXFP3
    Haugaard-Kedstrom, Linda M.
    Lee, Han Siean
    Jones, Maryon V.
    Song, Angela
    Rathod, Vishaal
    Hossain, Mohammed Akhter
    Bathgate, Ross A. D.
    Rosengren, K. Johan
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 293 (41) : 15765 - 15776
  • [18] Determining relaxin-3/RXFP3 activation by inhibition of forskolin induced cAMP assay
    Jayakody JPT
    Herr DR
    Dawe GS
    中国药理学与毒理学杂志, 2015, 29(S1) (S1) : 22 - 23
  • [19] STRUCTURAL MINIMIZATION OF THE NEUROPEPTIDE, RELAXIN-3, CONFERS SELECTIVITY AT ITS RXFP3 RECEPTOR
    Shabanpoor, Fazel
    Hossain, Mohammad Akhter
    Ryan, Philip J.
    Samuel, Chrishan S.
    Kocan, Martina
    Gundlach, Andrew L.
    Bathgate, Ross A. D.
    Separovic, Frances
    Wade, John D.
    BIOPOLYMERS, 2011, 96 (04) : 463 - 463
  • [20] Central relaxin-3 receptor (RXFP3) activation impairs social recognition and modulates ERK-phosphorylation in specific GABAergic amygdala neurons
    Hector Albert-Gasco
    Sandra Sanchez-Sarasua
    Sherie Ma
    Cristina García-Díaz
    Andrew L. Gundlach
    Ana M. Sanchez-Perez
    Francisco E. Olucha-Bordonau
    Brain Structure and Function, 2019, 224 : 453 - 469