Mechanisms of extracellular signal-regulated kinase (ERK) 1/2 phosphorylation following activation of relaxin family peptide receptor 3 (RXFP3) by human relaxin-3 (H3 relaxin).

被引:0
|
作者
van der Westhuizen, Emma T. [1 ]
Sexton, Patrick M. [1 ]
Summers, Roger J. [1 ]
机构
[1] Monash Univ, Dept Pharmacol, Monash, Vic 3800, Australia
来源
关键词
relaxin-3; G - protein coupled receptor; signal transduction;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:392 / 393
页数:2
相关论文
共 50 条
  • [1] H2 Relaxin Is a Biased Ligand Relative to H3 Relaxin at the Relaxin Family Peptide Receptor 3 (RXFP3)
    van der Westhuizen, Emma T.
    Christopoulos, Arthur
    Sexton, Patrick M.
    Wade, John D.
    Summers, Roger J.
    MOLECULAR PHARMACOLOGY, 2010, 77 (05) : 759 - 772
  • [2] Development of an ERK1/2 activation assay to determine relaxin-3/RXFP3 activation
    Jayakody JPT
    Dawe GS
    中国药理学与毒理学杂志, 2015, 29(S1) (S1) : 50 - 50
  • [3] Minimization of Human Relaxin-3 Leading to High-Affinity Analogues with Increased Selectivity for Relaxin-Family Peptide 3 Receptor (RXFP3) over RXFP1
    Shabanpoor, Fazel
    Hossain, Mohammad Alchter
    Ryan, Philip J.
    Belgi, Alessia
    Layfield, Sharon
    Kocan, Martina
    Zhang, Suode
    Samuel, Chrishan S.
    Gundlach, Andrew L.
    Bathgate, Ross A. D.
    Separovic, Frances
    Wade, John D.
    JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (04) : 1671 - 1681
  • [4] Orthosteric, Allosteric and Biased Signalling at the Relaxin-3 Receptor RXFP3
    Kocan, Martina
    Ang, Sheng Yu
    Summers, Roger J.
    NEUROCHEMICAL RESEARCH, 2016, 41 (03) : 610 - 619
  • [5] Orthosteric, Allosteric and Biased Signalling at the Relaxin-3 Receptor RXFP3
    Martina Kocan
    Sheng Yu Ang
    Roger J. Summers
    Neurochemical Research, 2016, 41 : 610 - 619
  • [6] AP-1 is activated by relaxin family peptides in cells expressing the relaxin family peptide receptor 3 (RXFP3)
    van der Westhuizen, Emma T.
    Sexton, Patrick M.
    Summers, Roger J.
    FASEB JOURNAL, 2008, 22
  • [7] Relaxin-3 receptor (Rxfp3) gene knockout mice display reduced running wheel activity: Implications for role of relaxin-3/RXFP3 signalling in sustained arousal
    Hosken, Ihaia T.
    Sutton, Steven W.
    Smith, Craig M.
    Gundlach, Andrew L.
    BEHAVIOURAL BRAIN RESEARCH, 2015, 278 : 167 - 175
  • [8] Relaxin-3 receptor (RXFP3) expression by gaba neurons in hippocampus and amygdala and effects of RXFP3 activation on behaviour
    Rytova, V.
    Nategh, M.
    Aumann, T. D.
    Albert-Gasco, H.
    Reid, C. A.
    Bathgate, R. A. D.
    Oloucha-Bordonau, F. E.
    Ma, S.
    Gundlach, A. L.
    JOURNAL OF NEUROCHEMISTRY, 2019, 150 : 205 - 205
  • [9] The Relaxin-3 Receptor, RXFP3, Is a Modulator of Aging-Related Disease
    Leysen, Hanne
    Walter, Deborah
    Clauwaert, Lore
    Hellemans, Lieselot
    van Gastel, Jaana
    Vasudevan, Lakshmi
    Martin, Bronwen
    Maudsley, Stuart
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (08)
  • [10] Novel single-chain ligands for the relaxin-3 receptor RXFP3
    Rosengren, K. J.
    Haugaard-Kedstroem, L. M.
    Jones, M.
    Clark, R. J.
    Bathgate, R. A. D.
    JOURNAL OF PEPTIDE SCIENCE, 2012, 18 : S48 - S48