Synthesis of a Series of Hydroxycarboxylic Acids as Standards for Oxidation of Nonanoic Acid

被引:13
作者
Rajabi, Mehdi [1 ]
Lanfranchi, Moreno [1 ]
Campo, Federica [1 ]
Panza, Luigi [1 ]
机构
[1] Univ Piemonte Orientale, Dipartimento Sci Farmaco, I-28100 Novara, Italy
关键词
macrolactone; IBX; natural products; hydroxycarboxylic acid; Grignard; BAEYER-VILLIGER OXIDATION; HYDROGEN-PEROXIDE; FATTY-ACIDS; CYTOCHROME-P450; KETONES;
D O I
10.1080/00397911.2013.853800
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of a series of nonanoic acids hydroxylated in terminal,omega-1,omega-2,omega-3 positions is described. These compounds will be employed as useful standards for the study of enzymatic and microbiological oxidation of nonanoic acid. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) for the following free supplemental resource(s): Full experimental and spectral details.]
引用
收藏
页码:1149 / 1154
页数:6
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