Difficult cannulation as defined by a prospective study of the Scandinavian Association for Digestive Endoscopy (SADE) in 907 ERCPs

被引:143
作者
Halttunen, Jorma [1 ]
Meisner, Soren [2 ]
Aabakken, Lars [3 ]
Arnelo, Urban [4 ]
Gronroos, Juha [5 ]
Hauge, Truls [6 ]
Kleveland, Per M. [7 ]
Schmidt, Palle Nordblad [8 ]
Saarela, Arto [9 ]
Swahn, Fredrik [4 ]
Toth, Ervin [10 ]
Mustonen, Harri [1 ]
Lohr, J. -Matthias [4 ]
机构
[1] Univ Helsinki, Cent Hosp, Dept Gastrointestinal & Gen Surg, Helsinki 00029, Hus, Finland
[2] Bispebjerg Hosp, DK-2400 Copenhagen, Denmark
[3] OUS Rikshosp, Oslo, Norway
[4] Karolinska Univ Sjukhuset, Gastroctr Kirurgi, Stockholm, Sweden
[5] Turku Univ Hosp, Div Digest Surg & Urol, FIN-20520 Turku, Finland
[6] Oslo Univ Hosp, Dept Gastroenterol, Oslo, Norway
[7] Reg Sykehuset, Med Avdelning, Trondheim, Norway
[8] Univ Copenhagen, Hvidovre Hosp, Dept Gastroenterol, DK-2650 Hvidovre, Denmark
[9] Oulu Univ Hosp, Dept Gastrointestinal Surg, Oulu, Finland
[10] Skane Univ Hosp, Endoscopy Unit, Malmo, Sweden
关键词
cannulation; ERCP; needle knife; sphincterotomy; BILE-DUCT CANNULATION; WIRE-GUIDED CANNULATION; PROSPECTIVE RANDOMIZED-TRIAL; NEEDLE-KNIFE SPHINCTEROTOMY; BILIARY CANNULATION; PRECUT SPHINCTEROTOMY; RETROGRADE CHOLANGIOPANCREATOGRAPHY; SELECTIVE CANNULATION; PANCREATITIS; STANDARD;
D O I
10.3109/00365521.2014.894120
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background. The definition of a "difficult" cannulation varies considerably in reports of endoscopic retrograde cholangiopancreatography (ERCP). Aims. To define a difficult cannulation, which translates into higher risk of post-ERCP pancreatitis. Patients and methods. Prospective consecutive recording of 907 cannulations in Scandinavian centers done by experienced endoscopists. Inclusion: indication for biliary access in patients with intact papilla. Exclusion: acute non-biliary and chronic pancreatitis at time of procedure. Results. The primary cannulation succeeded in 74.9%, with median values for time 0.88 min (53 s), with two attempts and with zero pancreatic passages or injections. The overall cannulation success was 97.4% and post-ERCP pancreatitis (PEP) rate was 5.3%. The median time for all successful cannulations was 1.55 min (range 0.02-94.2). If the primary cannulation succeeded, the pancreatitis rate was 2.8%; after secondary methods, it rose to 11.5%. Procedures lasting less than 5 min had a PEP rate of 2.6% versus 11.8% in those lasting longer. With one attempt, the PEP rate was 0.6%, with two 3.1%, with three to four 6.1%, and with five and more 11.9%. With one accidental pancreatic guide-wire passage, the risk of the PEP was 3.7%, and with two passages, it was 13.1%. Conclusions. If the increasing rate of PEP is taken as defining factor, the wire-guided cannulation of a native papilla can be considered difficult after 5 min, five attempts, and two pancreatic guide-wire passages when any of those limits is exceeded.
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页码:752 / 758
页数:7
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