Ventilator-associated pneumonia due to extensive drug-resistant Acinetobacter baumannii: Risk factors, clinical features, and outcomes

被引：58

作者：

Ozgur, Eylem Sercan ^{[1
]}

Horasan, Elif Sahin ^{[2
]}

Karaca, Kerem ^{[3
]}

Ersoz, Gulden ^{[2
]}

Atis, Sibel Nayci ^{[1
]}

Kaya, Ali ^{[2
]}

机构：

[1] Mersin Univ, Sch Med, Dept Chest Dis, TR-33079 Mersin, Turkey

[2] Mersin Univ, Sch Med, Dept Infect Dis, TR-33079 Mersin, Turkey

[3] Mersin Univ, Sch Med, Dept Cardiovasc Surg, TR-33079 Mersin, Turkey

来源：

AMERICAN JOURNAL OF INFECTION CONTROL | 2014年 / 42卷 / 02期

关键词：

Acinetobacter baumannii; Outcome; Simplified Acute Physiology Score II; SAPS II; Ventilator-associated pneumonia; PSEUDOMONAS-AERUGINOSA; INFECTION;

D O I：

10.1016/j.ajic.2013.09.003

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Acinetobacter baumannii is characterized by a rapid development of resistance to the commonly used antimicrobial agents. We investigated the risk factors, clinical features, and outcomes in ventilator-associated pneumonia (VAP) caused by extensive drug-resistant Acinetobacter baumannii (XDRAB). Clinical parameters and overall in-hospital mortality rates were compared between the VAP with and without XDRAB infection groups. This study showed that VAP caused by XDRAB was not associated with in-hospital mortality. However, it was related to high Simplified Acute Physiology Score II scores and increasing durations of hospital stays. Copyright (C) 2014 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

引用

收藏

页码：206 / 208

页数：3

相关论文

共 14 条

[1] Guidelines for the management, of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia [J].

不详 .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2005, 171 (04) :388-416

[2]

[Anonymous], PERF STAND ANT SU S

[3]

[Anonymous], 2010, J INFECT DEV COUNTR

[4] Epidemiological investigation after hospitalising a case with pandrug-resistant Acinetobacter baumannii infection [J].

Chuang, Y. -Y. ;

Huang, Y. -C. ;

Lin, C. -H. ;

Su, L. -H. ;

Wu, C. -T. .

JOURNAL OF HOSPITAL INFECTION, 2009, 72 (01) :30-35

[5] NOSOCOMIAL PNEUMONIA IN PATIENTS RECEIVING CONTINUOUS MECHANICAL VENTILATION - PROSPECTIVE ANALYSIS OF 52 EPISODES WITH USE OF A PROTECTED SPECIMEN BRUSH AND QUANTITATIVE CULTURE TECHNIQUES [J].

FAGON, JY ;

CHASTRE, J ;

DOMART, Y ;

TROUILLET, JL ;

PIERRE, J ;

DARNE, C ;

GIBERT, C .

AMERICAN REVIEW OF RESPIRATORY DISEASE, 1989, 139 (04) :877-884

[6] Risk factors for the isolation of multi-drug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa:: a systematic review of the literature [J].

Falagas, M. E. ;

Kopterides, P. .

JOURNAL OF HOSPITAL INFECTION, 2006, 64 (01) :7-15

[7] Emergence of resistance to carbapenems in Acinetobacter baumannii in Europe: clinical impact and therapeutic options [J].

Kempf, Marie ;

Rolain, Jean-Marc .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2012, 39 (02) :105-114

[8] A NEW SIMPLIFIED ACUTE PHYSIOLOGY SCORE (SAPS-II) BASED ON A EUROPEAN NORTH-AMERICAN MULTICENTER STUDY [J].

LEGALL, JR ;

LEMESHOW, S ;

SAULNIER, F .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1993, 270 (24) :2957-2963

[9] Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance [J].

Magiorakos, A. -P. ;

Srinivasan, A. ;

Carey, R. B. ;

Carmeli, Y. ;

Falagas, M. E. ;

Giske, C. G. ;

Harbarth, S. ;

Hindler, J. F. ;

Kahlmeter, G. ;

Olsson-Liljequist, B. ;

Paterson, D. L. ;

Rice, L. B. ;

Stelling, J. ;

Struelens, M. J. ;

Vatopoulos, A. ;

Weber, J. T. ;

Monnet, D. L. .

CLINICAL MICROBIOLOGY AND INFECTION, 2012, 18 (03) :268-281

[10] Acinetobacter baumannii 2002-2008: Increase of Carbapenem-Associated Multiclass Resistance in the United States [J].

Mera, Robertino M. ;

Miller, Linda A. ;

Amrine-Madsen, Heather ;

Sahm, Daniel F. .

MICROBIAL DRUG RESISTANCE, 2010, 16 (03) :209-215