Rigid, self-assembled hydrogel composed of a modified aromatic dipeptide

被引：718
作者：
Mahler, Assaf
Reches, Meital
Rechter, Meirav
Cohen, Smadar
Gazit, Ehud [1 ]
机构：
[1] Tel Aviv Univ, George S Wise Fac Life Sci, Dept Mol Microbiol & Biotechnol, IL-69978 Tel Aviv, Israel
[2] Ben Gurion Univ Negev, Dept Biotechnol Engn, IL-84105 Beer Sheva, Israel
来源：
ADVANCED MATERIALS | 2006年 / 18卷 / 11期
关键词：
D O I：
10.1002/adma.200501765
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple dipeptide self-assembles into a biocompatible hydrogel (see figure and inside cover). This novel biomaterial is extremely simple to prepare and has a remarkable rigidity. It is very stable under extreme conditions, can be injected, and can be shaped according to the vessel it has been assembled in. The hydrogel allows a wide variety of possible biomedical applications including tissue engineering, axonal regeneration, and controlled drug release.
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页码：1365 / +
页数：7
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