Thermal properties of copoly(L-lactic acid/glycolic acid) by direct melt polycondensation

被引：7
|
作者：
Lan, Ping [1 ]
Jia, Lv [1 ]
机构：
[1] Jiaxing Univ, Jiaxing 314001, Zhejiang, Peoples R China
来源：
JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY | 2006年 / 43卷 / 11期
关键词：
melt polymerization; L-lactic acid; glycolic acid; poly(L-lactic acid-co-glycolic acid) (PLGA); thermal properties; racemization;
D O I：
10.1080/10601320600941284
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Poly( L-lactic acid-co-glycolic acid) ( PLGA) was prepared from hydroxy-acids with melt polymerization. In this way, the copoly( L-LA/GA) ( PLGA) was synthesized directly using a binary catalyst ( tin chloride dihydrate/p-toluenesulfonic acid). The thermal properties of PLGA were studied by differential scanning calorimetry (DSC) and nuclear magnetic resonance (NMR). The results show that the melting point of PLGA decreases with increasing mole fraction of GA units in the copolymer. In addition, the melting point of polymer also decreases with increasing degree of racemization of the polymer.
引用
收藏
页码：1887 / 1894
页数：8
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