Toward larger chemical libraries: Encoding with fluorescent colloids in combinatorial chemistry

被引:137
作者
Battersby, BJ
Bryant, D
Meutermans, W
Matthews, D
Smythe, ML
Trau, M [1 ]
机构
[1] Univ Queensland, Dept Chem, St Lucia, Qld 4072, Australia
[2] Univ Queensland, Dept Math, St Lucia, Qld 4072, Australia
[3] Univ Queensland, Ctr Drug Design & Dev, St Lucia, Qld 4072, Australia
关键词
D O I
10.1021/ja993634i
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
[No abstract available]
引用
收藏
页码:2138 / 2139
页数:2
相关论文
共 21 条
[1]   Identification of novel antitumor agents from mixture-based synthetic combinatorial libraries using cell-based assays [J].
Appel, JR ;
Johnson, J ;
Narayanan, VL ;
Houghten, RA .
MOLECULAR DIVERSITY, 1998, 4 (02) :91-102
[2]   ENCODED COMBINATORIAL CHEMISTRY [J].
BRENNER, S ;
LERNER, RA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (12) :5381-5383
[3]   SYNTHESIS OF SUPPORT-BOUND PEPTIDES CARRYING COLOR LABELS [J].
CAMPIAN, E ;
SEBESTYEN, F ;
MAJOR, F ;
FURKA, A .
DRUG DEVELOPMENT RESEARCH, 1994, 33 (02) :98-101
[4]   Encoding methods for combinatorial chemistry [J].
Czarnik, AW .
CURRENT OPINION IN CHEMICAL BIOLOGY, 1997, 1 (01) :60-66
[5]   Tagging in combinatorial chemistry: The use of coloured and fluorescent beads [J].
Egner, BJ ;
Rana, S ;
Smith, H ;
Bouloc, N ;
Frey, JG ;
Brocklesby, WS ;
Bradley, M .
CHEMICAL COMMUNICATIONS, 1997, (08) :735-736
[6]   Purine based combinatorial chemistry: Solution phase simultaneous addition of functionalities. Iterative deconvolution by orthogonal protection to a single compound with potent antibacterial activity. [J].
Fraser, AS ;
Kawasaki, AM ;
Cook, PD .
NUCLEOSIDES & NUCLEOTIDES, 1999, 18 (4-5) :1087-1089
[7]   GENERAL-METHOD FOR RAPID SYNTHESIS OF MULTICOMPONENT PEPTIDE MIXTURES [J].
FURKA, A ;
SEBESTYEN, F ;
ASGEDOM, M ;
DIBO, G .
INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 1991, 37 (06) :487-493
[8]   GENERATION AND USE OF SYNTHETIC PEPTIDE COMBINATORIAL LIBRARIES FOR BASIC RESEARCH AND DRUG DISCOVERY [J].
HOUGHTEN, RA ;
PINILLA, C ;
BLONDELLE, SE ;
APPEL, JR ;
DOOLEY, CT ;
CUERVO, JH .
NATURE, 1991, 354 (6348) :84-86
[9]   Mixture-based synthetic combinatorial libraries [J].
Houghten, RA ;
Pinilla, C ;
Appel, JR ;
Blondelle, SE ;
Dooley, CT ;
Eichler, J ;
Nefzi, A ;
Ostresh, JM .
JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (19) :3743-3778
[10]  
Hunter R.J., 1986, FDN COLLOID SCI