Drug metabolism in the skin

被引：17

作者：

Baron, Jens M. ^{[1
]}

Merk, Hans F. ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Univ Hosp, Dept Dermatol, Pauwelsstr 30, D-52074 Aachen, Germany

来源：

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY | 2001年 / 1卷 / 04期

关键词：

D O I：

10.1097/00130832-200108000-00002

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The skin performs a wide range of active metabolic functions including xenobiotic metabolism involving metabolizing enzymes specific to the skin. In this review we focus on the role of drug metabolism: (i) in allergic reactions to substances of low molecular weight; (ii) in cutaneous vitamin A and D-3 metabolism and its modulation; (iii) in the interaction of transport and metabolic enzymes in skin cells; and (iv) on novel tools for the measurement of drug metabolism in various compartments of the human skin. (C) 2001 Lippincott Williams & Wilkins.

引用

页码：287 / 291

页数：5

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