Standardizing ADOS Domain Scores: Separating Severity of Social Affect and Restricted and Repetitive Behaviors

被引:197
作者
Hus, Vanessa [1 ]
Gotham, Katherine [2 ]
Lord, Catherine [3 ]
机构
[1] Univ Michigan, Dept Psychol, Ann Arbor, MI 48109 USA
[2] Vanderbilt Univ, Vanderbilt Kennedy Ctr, Nashville, TN 37235 USA
[3] Weill Cornell Med Coll, Ctr Autism & Developing Brain, White Plains, NY USA
基金
美国国家卫生研究院;
关键词
Autism spectrum disorders; Autism Diagnostic Observation Schedule; Severity; Social Affect; Restricted and Repetitive Behaviors; AUTISM; CRITERIA;
D O I
10.1007/s10803-012-1719-1
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Standardized Autism Diagnostic Observation Schedule (ADOS) scores provide a measure of autism severity that is less influenced by child characteristics than raw totals (Gotham et al. in Journal of Autism and Developmental Disorders, 39(5), 693-705 2009). However, these scores combine symptoms from the Social Affect (SA) and Restricted and Repetitive Behaviors (RRB) domains. Separate calibrations of each domain would provide a clearer picture of ASD dimensions. The current study separately calibrated raw totals from the ADOS SA and RRB domains. Standardized domain scores were less influenced by child characteristics than raw domain totals, thereby increasing their utility as indicators of Social-Communication and Repetitive Behavior severity. Calibrated domain scores should facilitate efforts to examine trajectories of ASD symptoms and links between neurobiological and behavioral dimensions.
引用
收藏
页码:2400 / 2412
页数:13
相关论文
共 28 条
[1]  
American Psychiatric Association, 2011, DSM 5 DEV 09 AUT SPE
[2]  
[Anonymous], 2000, Diagnostic and Statistical Manual of Mental Disorders, DOI DOI 10.1176/DSM10.1176/APPI.BOOKS.9780890420249.DSM-IV-TR
[3]  
[Anonymous], 2012, INT CLASS DIS 11 REV
[4]  
[Anonymous], J CHILD PSY IN PRESS
[5]  
Cohen J., 1988, Statistical Power Analysis for the Behavioral Sciences
[6]  
Constantino J. N., 2012, SOCIAL RESPONSIVENES
[7]   Deficits in reciprocal social behavior in male twins: Evidence for a genetically independent domain of psychopathology [J].
Constantino, JN ;
Hudziak, JJ ;
Todd, RD .
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2003, 42 (04) :458-467
[8]   Aberrant Striatal Functional Connectivity in Children with Autism [J].
Di Martino, Adriana ;
Kelly, Clare ;
Grzadzinski, Rebecca ;
Zuo, Xi-Nian ;
Mennes, Maarten ;
Angeles Mairena, Maria ;
Lord, Catherine ;
Castellanos, F. Xavier ;
Milham, Michael P. .
BIOLOGICAL PSYCHIATRY, 2011, 69 (09) :847-856
[9]   Reward Circuitry Function in Autism During Face Anticipation and Outcomes [J].
Dichter, Gabriel S. ;
Richey, J. Anthony ;
Rittenberg, Alison M. ;
Sabatino, Antoinette ;
Bodfish, James W. .
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 2012, 42 (02) :147-160
[10]   THE PRE-LINGUISTIC AUTISM DIAGNOSTIC OBSERVATION SCHEDULE [J].
DILAVORE, PC ;
LORD, C ;
RUTTER, M .
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 1995, 25 (04) :355-379