Minicolumnar pathology in dyslexia

被引：50
作者：
Casanova, MF
Buxhoeveden, DP
Cohen, M
Switala, AE
Roy, EL
机构：
[1] Downtown Vet Affairs Med Ctr 24, Augusta, GA 30904 USA
[2] Med Coll Georgia, Dept Psychiat & Neurol, Augusta, GA 30912 USA
[3] Med Coll Georgia, Dept Neurol, Augusta, GA 30912 USA
来源：
ANNALS OF NEUROLOGY | 2002年 / 52卷 / 01期
关键词：
D O I：
10.1002/ana.10226
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The minicolumn is an anatomical and functional unit of the brain whose genesis accrues from germinal cell divisions in the ventricular zone of the brain. Disturbances in the morphometry of minicolumns have been demonstrated recently for both autism and Down's syndrome. We report minicolumnar abnormalities in the brain of a dyslexic patient. The corresponding developmental disturbance (ie, large minicolumns) could account for the perceptual errors observed in dyslexia.
引用
收藏
页码：108 / 110
页数：3
相关论文
共 20 条
[1]  
Buxhoeveden D, 1996, ANAT EMBRYOL, V194, P23
[2]   Quantitative comparison of radial cell columns in children with Down's syndrome and controls [J].
Buxhoeveden, D ;
Fobbs, A ;
Roy, E ;
Casanova, MF .
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2002, 46 :76-81
[3]  
BUXHOEVEDEN D, 2001, P SUMM AM PSYCH ASS, P728
[4]   Quantitative analysis of cell columns in the cerebral cortex [J].
Buxhoeveden, DP ;
Switala, AE ;
Roy, E ;
Casanova, MF .
JOURNAL OF NEUROSCIENCE METHODS, 2000, 97 (01) :7-17
[5]   Morphological differences between minicolumns in human and nonhuman primate cortex [J].
Buxhoeveden, DP ;
Switala, AE ;
Roy, E ;
Litaker, M ;
Casanova, MF .
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY, 2001, 115 (04) :361-371
[6]   Lateralization of minicolumns in human planum temporale is absent in nonhuman primate cortex [J].
Buxhoeveden, DR ;
Switala, AE ;
Litaker, M ;
Roy, E ;
Casanova, MF .
BRAIN BEHAVIOR AND EVOLUTION, 2001, 57 (06) :349-358
[7]   Minicolumnar pathology in autism [J].
Casanova, MF ;
Buxhoeveden, DP ;
Switala, AE ;
Roy, E .
NEUROLOGY, 2002, 58 (03) :428-432
[8]  
Childs J A, 1997, J Neurosci Nurs, V29, P244
[9]   CYTOARCHITECTONIC ABNORMALITIES IN DEVELOPMENTAL DYSLEXIA - CASE-STUDY [J].
GALABURDA, AM ;
KEMPER, TL .
ANNALS OF NEUROLOGY, 1979, 6 (02) :94-100
[10]   The caudal infrasylvian surface in dyslexia - Novel magnetic resonance imaging-based findings [J].
Green, RL ;
Hutsler, JJ ;
Loftus, WC ;
Tramo, MJ ;
Thomas, CE ;
Silberfarb, AW ;
Nordgren, RE ;
Nordgren, RA ;
Gazzaniga, MS .
NEUROLOGY, 1999, 53 (05) :974-981
12