NBS-promoted halosulfonylation of terminal alkynes: highly regio- and stereoselective synthesis of (E)-β-halo vinylsulfones

被引：65

作者：

Gao, Yang ^{[1
]}

Wu, Wanqing ^{[1
]}

Huang, Yubing ^{[1
]}

Huang, Kefan ^{[1
]}

Jiang, Huanfeng ^{[1
]}

机构：

[1] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2014年 / 1卷 / 04期

基金：

中国国家自然科学基金;

关键词：

CATALYZED ALLYLIC SULFONYLATION; ATOM ECONOMY; VINYL SULFONES; ORGANIC-SYNTHESIS; GREEN CHEMISTRY; SULFONYLHYDRAZIDES; INHIBITORS; DIFUNCTIONALIZATION; ACETYLENES; EFFICIENCY;

D O I：

10.1039/c3qo00075c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient NBS-promoted method for the synthesis of (E)-beta-halo vinylsulfones has been developed. The present protocol went through an environmentally friendly metal-free process to achieve the halosulfonylation of terminal alkynes with high selectivity.

引用

页码：361 / 364

页数：4

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