Store overload-induced Ca2+ release as a triggering mechanism for CPVT and MH episodes caused by mutations in RYR and CASQ genes

被引：75
作者：
MacLennan, David H. [1 ]
Chen, S. R. Wayne [2 ,3 ,4 ]
机构：
[1] Univ Toronto, Charles H Best Inst, Banting & Best Dept Med Res, Toronto, ON M5G 1L6, Canada
[2] Univ Calgary, Libin Cardiovasc Inst Alberta, Dept Physiol, Calgary, AB T2N 4N1, Canada
[3] Univ Calgary, Libin Cardiovasc Inst Alberta, Dept Biophys & Biochem, Calgary, AB T2N 4N1, Canada
[4] Univ Calgary, Libin Cardiovasc Inst Alberta, Dept Mol Biol, Calgary, AB T2N 4N1, Canada
来源：
JOURNAL OF PHYSIOLOGY-LONDON | 2009年 / 587卷 / 13期
基金：
美国国家卫生研究院; 加拿大健康研究院;
关键词：
POLYMORPHIC VENTRICULAR-TACHYCARDIA; CENTRAL CORE DISEASE; SARCOPLASMIC-RETICULUM; LUMINAL CA2+; MALIGNANT HYPERTHERMIA; CARDIAC CALSEQUESTRIN; RYANODINE-RECEPTORS; CALCIUM-RELEASE; SUDDEN-DEATH; INCREASE;
D O I：
10.1113/jphysiol.2009.172155
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
引用
收藏
页码：3113 / 3115
页数：3
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