BURSTING AND SYNCHRONY IN NETWORKS OF MODEL NEURONS

被引:0
作者
Geier, C. [1 ]
Rothkegel, A. [1 ]
Lehnertz, K. [1 ]
机构
[1] Univ Bonn, Dept Epileptol, D-53105 Bonn, Germany
来源
RECENT ADVANCES IN PREDICTING AND PREVENTING EPILEPTIC SEIZURES | 2013年
关键词
Bursting; Epilepsy; Synchronization; Network; Small-World; EPILEPSY; SEIZURES; ILAE;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Bursting neurons are considered to be a potential cause of over-excitability and seizure susceptibility. The functional influence of these neurons in extended epileptic networks is still poorly understood. There is mounting evidence that the dynamics of neuronal networks is influenced not only by neuronal and synaptic properties but also by network topology. We investigate numerically the influence of different neuron dynamics on global synchrony in neuronal networks with complex connection topologies.
引用
收藏
页码:108 / 116
页数:9
相关论文
共 18 条
[1]   Plasticity of intrinsic neuronal properties in CNS disorders [J].
Beck, Heinz ;
Yaari, Yoel .
NATURE REVIEWS NEUROSCIENCE, 2008, 9 (05) :357-369
[2]   Interaction of Cellular and Network Mechanisms in Spatiotemporal Pattern Formation in Neuronal Networks [J].
Bogaard, Andrew ;
Parent, Jack ;
Zochowski, Michal ;
Booth, Victoria .
JOURNAL OF NEUROSCIENCE, 2009, 29 (06) :1677-1687
[3]   Breaking synchrony by heterogeneity in complex networks [J].
Denker, M ;
Timme, M ;
Diesmann, M ;
Wolf, F ;
Geisel, T .
PHYSICAL REVIEW LETTERS, 2004, 92 (07)
[4]   Topological determinants of epileptogenesis in large-scale structural and functional models of the dentate gyrus derived from experimental data [J].
Dyhrfjeld-Johnsen, Jonas ;
Santhakumar, Vijayalakshmi ;
Morgan, Robert J. ;
Huerta, Ramon ;
Tsimring, Lev ;
Soltesz, Ivan .
JOURNAL OF NEUROPHYSIOLOGY, 2007, 97 (02) :1566-1587
[5]   Report of the ILAE Classification Core Group [J].
Engel, Jerome, Jr. .
EPILEPSIA, 2006, 47 (09) :1558-1568
[6]  
Engel JJ., 2007, EPILEPSY COMPREHENSI, V2nd
[7]   Internetwork and intranetwork communications during bursting dynamics: Applications to seizure prediction [J].
Feldt, S. ;
Osterhage, H. ;
Mormann, F. ;
Lehnertz, K. ;
Zochowski, M. .
PHYSICAL REVIEW E, 2007, 76 (02)
[8]   Epileptic seizures and epilepsy: Definitions proposed by the International League against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) [J].
Fisher, RS ;
Boas, WV ;
Blume, W ;
Elger, C ;
Genton, P ;
Lee, P ;
Engel, J .
EPILEPSIA, 2005, 46 (04) :470-472
[9]   Simple model of spiking neurons [J].
Izhikevich, EM .
IEEE TRANSACTIONS ON NEURAL NETWORKS, 2003, 14 (06) :1569-1572
[10]   Bursts as a unit of neural information: Making unreliable synapses reliable [J].
Lisman, JE .
TRENDS IN NEUROSCIENCES, 1997, 20 (01) :38-43