Thyroid MALT lymphoma in patients with a compressive goiter

被引:15
作者
Earnest, Lisa M.
Cooper, David S. [1 ]
Sciubba, James J.
Tufano, Ralph P.
机构
[1] Johns Hopkins Univ, Sch Med, Div Endocrinol, Sinai Hosp Baltimore, Baltimore, MD 21215 USA
[2] Johns Hopkins Univ, Sch Med, Div Head & Neck Surg, Dept Otolaryngol Head & Neck Surg, Baltimore, MD USA
[3] Johns Hopkins Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Div Oral Dent Med, Baltimore, MD USA
[4] Johns Hopkins Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Div Pathol, Baltimore, MD USA
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2006年 / 28卷 / 08期
关键词
thyroid lymphoma; MALT; compressive goiter;
D O I
10.1002/hed.20424
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background. Mucosa-associated lymphoid tissue (MALT) lymphomas account for less than 1% of all primary thyroid malignancies. They typically arise as neoplastic transfermations within areas of autoimmune thyroiditis. Although they tend to have an indolent course, these lymphomas present a diagnostic challenge requiring a high level of suspicion in patients at increased risk of development. Methods. We retrospectively reviewed 3 cases of primary MALT thyroid lymphoma discovered in patients with a compressive goiter. This represents the experience at a single institution from 1996 to 2005, Hospital and clinic records were reviewed to identify the workup, treatment, and outcome. Results. One of 3 patients underwent preoperative fine-needle aspiration (FNA). All patients underwent total thyroidectomy to relieve compressive symptoms, and the final pathology revealed MALT lymphoma. Two patients subsequently underwent radiation therapy. All patients are alive without evidence of disease recurrence. Conclusions. These cases are notable for the unexpected presentation of MALT lymphoma within a compressive goiter. (c) 2006 Wiley Periodicals, Inc.
引用
收藏
页码:765 / 770
页数:6
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