Potential of Ginkgo biloba L. leaves in the management of hyperglycemia and hypertension using in vitro models

被引：52

作者：

Pinto, Marcia Da Silva ^{[2
]}

Kwon, Young-In ^{[1
]}

Apostolidis, Emmanouil ^{[1
]}

Lajolo, Franco Maria ^{[2
]}

Genovese, Maria Ines ^{[2
]}

Shetty, Kalidas ^{[1
]}

机构：

[1] Univ Massachusetts, Lab Food Biotechnol, Dept Food Sci, Amherst, MA 01003 USA

[2] Univ Sao Paulo, Lab Quim Bioquim & Biol Mol Alimentos, Dept Alimentos & Nutr Expt, FCF, BR-05508900 Sao Paulo, Brazil

来源：

BIORESOURCE TECHNOLOGY | 2009年 / 100卷 / 24期

关键词：

Ginkgo biloba L; Antioxidant activity; Diabetes; Hypertension; Phenolics; ALPHA-AMYLASE; FLAVONOID QUERCETIN; EXTRACT EGB-761; GLOBAL BURDEN; GREEN TEA; GLUCOSIDASE; HEALTHY; INGESTION; PREVENTION; INCREASES;

D O I：

10.1016/j.biortech.2009.07.021

中图分类号：

S2 [农业工程];

学科分类号：

0828 ;

摘要：

Leaves from four different Ginkgo biloba L. trees (1 and 2 - females; 3 and 4 - males), grown at the same conditions, were collected during a period of 5 months (from June to October, 2007). Water and 12% ethanol extracts were analyzed for total phenolics content, antioxidant activity, phenolic profile, and the potential in vitro inhibitory effects on alpha-amylase, alpha-glucosidase, and Angiotensin I-Converting Enzyme (ACE) enzymes related to the management of diabetes and hypertension. The results indicated a significant difference among the trees in all functional benefits evaluated in the leaf extracts and also found important seasonal variation related to the same functional parameters. In general, the aqueous extracts had higher total phenolic content than the ethanolic extracts. Also, no correlation was found between total phenolics and antioxidant activity. In relation to the ACE inhibition, only ethanolic extracts had inhibitory activity. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：6599 / 6609

页数：11

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