Dual Antiplatelet Therapy in the Anticoagulated Patient Undergoing Percutaneous Coronary Intervention Risks, Benefits, and Unanswered Questions

被引：2
作者：
Bennaghmouch, N. [1 ]
Dewilde, W. J. M. [2 ]
Ten Berg, J. M. [1 ]
机构：
[1] St Antonius Hosp Nieuwegein, Dept Cardiol, NL-3435 CM Nieuwegein, Netherlands
[2] Amphia Hosp Breda, Dept Cardiol, NL-4818 CK Breda, Netherlands
来源：
CURRENT CARDIOLOGY REPORTS | 2014年 / 16卷 / 12期
关键词：
Percutaneous coronary intervention; Atrial fibrillation; Acute coronary syndrome; Triple therapy; Oral anticoagulation; Dual antiplatelet therapy; TRIPLE ANTITHROMBOTIC THERAPY; ATRIAL-FIBRILLATION PATIENTS; 2011 ACCF/AHA/SCAI GUIDELINE; RHYTHM ASSOCIATION EHRA; COLLEGE-OF-CARDIOLOGY; DRUG-ELUTING STENTS; FACTOR XA INHIBITOR; LONG-TERM DURATION; ORAL ANTICOAGULATION; MYOCARDIAL-INFARCTION;
D O I：
10.1007/s11886-014-0548-6
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A commonly encountered scenario is the patient with atrial fibrillation (AF) on oral anticoagulation (OAC) who either develops an acute coronary syndrome or has to undergo percutaneous coronary intervention with stent placement. In such patients, separate indications suggest combining OAC and dual antiplatelet therapy (DAPT). This approach, however, increases the risk of bleeding as well as thromboembolic risk if bleeding does not occur. For optimal clinical results, the risks and benefits of all possible treatment options should be determined based on the best available data. This review provides an overview of the most recent data regarding the optimal treatment of AF patients with an indication for combined treatment with OAC and DAPT.
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页数：10
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