GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information

被引：359

作者：

Nogales-Cadenas, Ruben ^{[1
]}

Carmona-Saez, Pedro ^{[1
]}

Vazquez, Miguel ^{[2
]}

Vicente, Cesar ^{[1
]}

Yang, Xiaoyuan ^{[1
]}

Tirado, Francisco ^{[1
]}

Maria Carazo, Jose ^{[3
]}

Pascual-Montano, Alberto ^{[1
]}

机构：

[1] Univ Complutense Madrid, Comp Architecture Dept, Madrid, Spain

[2] Univ Complutense Madrid, Software Engn Dept, Madrid, Spain

[3] CNB CSIC, Natl Biotechnol Ctr, Biocomp Unit, Madrid, Spain

来源：

NUCLEIC ACIDS RESEARCH | 2009年 / 37卷

关键词：

EXPRESSION; TOOLS; DISCOVERY; SYSTEMS;

D O I：

10.1093/nar/gkp416

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

GeneCodis is a web server application for functional analysis of gene lists that integrates different sources of information and finds modular patterns of interrelated annotations. This integrative approach has proved to be useful for the interpretation of high-throughput experiments and therefore a new version of the system has been developed to expand its functionality and scope. GeneCodis now expands the functional information with regulatory patterns and user-defined annotations, offering the possibility of integrating all sources of information in the same analysis. Traditional singular enrichment is now permitted and more organisms and gene identifiers have been added to the database. The application has been re-engineered to improve performance, accessibility and scalability. In addition, GeneCodis can now be accessed through a public SOAP web services interface, enabling users to perform analysis from their own scripts and workflows. The application is freely available at http://genecodis.dacya.ucm.es

引用

页码：W317 / W322

页数：6

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