Regio- and stereoselective synthesis of vicinal fluorohydrins

被引：54

作者：

Haufe, G ^{[1
]}

机构：

[1] Univ Munster, Inst Organ Chem, D-48149 Munster, Germany

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2004年 / 125卷 / 06期

关键词：

condensation; enzyme-catalysis; epoxides; fluorohydrins; fluoroketones; hydrofluorination; reduction; resolution; ring opening; stereoselectivity; synthesis;

D O I：

10.1016/j.jfluchem.2004.01.023

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Vicinal fluorohydrins are useful building blocks as well as important targets for synthesis of bioactive compounds or new materials. This review gives an overview on regio- and stereoselective, particularly enantioselective, syntheses of such compounds by building block methods, reduction of alpha-fluoro carbonyl compounds and ring opening of epoxides with hydrofluorinating reagents. Resolution of racemic vicinal fluorohydrins using enzyme-catalyzed reactions will also be discussed in detail. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：875 / 894

页数：20

共 50 条

[11] Regio- and stereoselective synthesis of glycosyl phosphinic acids
Tzokov, SB
Devedjiev, IT
Petkov, DD
JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (01): : 12 - 13
[12] Regio- and Stereoselective Multisubstituted Enol Ester Synthesis
Okamoto, Noriko
Miwa, Yoshihisa
Minami, Hideki
Takeda, Kei
Yanada, Reiko
JOURNAL OF ORGANIC CHEMISTRY, 2011, 76 (21): : 9133 - 9138
[13] Theoretical analysis of the regio- and stereoselective synthesis of spiroisoxazolines
Nivedita Acharjee
Journal of Molecular Modeling, 2020, 26
[14] Regio- and Stereoselective Hydrophosphorylation of Ynamides for the Synthesis of β-Aminovinylphosphine Oxides
Huang, Hai
Zhu, Hongjun
Kang, Jun Yong
ORGANIC LETTERS, 2018, 20 (09) : 2778 - 2781
[15] Regio- and stereoselective synthesis of α-hydroxy-β-azido tetrazoles
Quinodoz, Pierre
Lo, Cheikh
Kletskii, Mikhail
Burov, Oleg
Marrot, Jerome
Couty, Francois
ORGANIC CHEMISTRY FRONTIERS, 2015, 2 (05): : 492 - 496
[16] Regio- and Stereoselective Synthesis of Multisubstituted Vinylsilanes via Zirconacycles
Nishihara, Yasushi
Saito, Daisuke
Tanemura, Kenki
Noyori, Shintaro
Takagi, Kentaro
ORGANIC LETTERS, 2009, 11 (16) : 3546 - 3549
[17] Regio- and stereoselective synthesis of α,β-dehydro-β-amino esters
Li, Dafeng
Li, Jian
Jia, Xueshun
JOURNAL OF CHEMICAL RESEARCH, 2008, (08) : 434 - 436
[18] Regio- and stereoselective synthesis of LNA guanine nucleosides.
Rosenhohm, C
Pedersen, DS
Koch, T
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 224 : U173 - U173
[19] Copper-Catalyzed Double Borylation of Silylacetylenes: Highly Regio- and Stereoselective Synthesis of Syn-Vicinal Diboronates
Jung, Ho-Young
Yun, Jaesook
ORGANIC LETTERS, 2012, 14 (10) : 2606 - 2609
[20] Regio- and stereoselective synthesis of 4′-thiaspiroacetals from carbohydrates
Bartolozzi, A
Capozzi, G
Falciani, C
Menichetti, S
Nativi, C
Bacialli, AP
JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (17): : 6490 - 6494

← 1 2 3 4 5 →