An Overview of Live Attenuated Recombinant Pseudorabies Viruses for Use as Novel Vaccines

被引：61

作者：

Dong, Bo ^{[1
]}

Zarlenga, Dante S. ^{[2
]}

Ren, Xiaofeng ^{[1
]}

机构：

[1] Northeast Agr Univ, Dept Vet Prevent Med, Coll Vet Med, Harbin 150030, Peoples R China

[2] ARS, Anim Parasit Dis Lab, Beltsville, MD 20705 USA

来源：

JOURNAL OF IMMUNOLOGY RESEARCH | 2014年 / 2014卷

关键词：

RESPIRATORY SYNDROME VIRUS; CLASSICAL SWINE-FEVER; ADENOVIRUS EXPRESSING GP5; MOUTH-DISEASE VIRUS; PORCINE-CIRCOVIRUS; PROTECTIVE EFFICACY; AUJESZKYS-DISEASE; GENE-EXPRESSION; HOG-CHOLERA; HA GENE;

D O I：

10.1155/2014/824630

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Pseudorabies virus (PRV) is a double-stranded, DNA-based swine virus with a genome approximating 150 kb in size. PRV has many nonessential genes which can be replaced with genes encoding heterologous antigens but without deleterious effects on virus propagation. Recombinant PRVs expressing both native and foreign antigens are able to stimulate immune responses. In this paper, we review the current status of live attenuated recombinant PRVs and live PRV-based vector vaccines with potential for controlling viral infections in animals.

引用

页数：10

共 74 条

[1] Isolation of porcine circovirus-like viruses from pigs with a wasting disease in the USA and Europe [J].

Allan, GM ;

McNeilly, F ;

Kennedy, S ;

Daft, B ;

Clarke, EG ;

Ellis, JA ;

Haines, DM ;

Meehan, BM ;

Adair, BM .

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 1998, 10 (01) :3-10

[2] Construction and Characterization of a Recombinant Canine Adenovirus Expressing GP5 and M proteins of Porcine Reproductive and Respiratory Syndrome Virus [J].

Cai, Jinshun ;

Ma, Yonghe ;

Li, Jiaying ;

Yan, Changguo ;

Hu, Rongliang ;

Zhang, Jiabao .

JOURNAL OF VETERINARY MEDICAL SCIENCE, 2010, 72 (08) :1035-1040

[3] A novel recombinant pseudorabies virus expressing parvovirus VP2 gene: Immunogenicity and protective efficacy in swine [J].

Chen, Yang ;

Guo, Wanzhu ;

Xu, Zhiwen ;

Yan, Qigui ;

Luo, Yan ;

Shi, Qian ;

Chen, Dishi ;

Zhu, Ling ;

Wang, Xiaoyu .

VIROLOGY JOURNAL, 2011, 8

[4] Co-translational, intraribosomal cleavage of polypeptides by the foot-and-mouth disease virus 2A peptide [J].

de Felipe, P ;

Hughes, LE ;

Ryan, MD ;

Brown, JD .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (13) :11441-11448

[5] Current knowledge on the structural proteins of porcine reproductive and respiratory syndrome (PRRS) virus: comparison of the North American and European isolates [J].

Dea, S ;

Gagnon, CA ;

Mardassi, H ;

Pirzadeh, B ;

Rogan, D .

ARCHIVES OF VIROLOGY, 2000, 145 (04) :659-688

[6] Evolution of foot-and-mouth disease virus [J].

Domingo, E ;

Escarmís, C ;

Baranowski, E ;

Ruiz-Jarabo, CM ;

Carrillo, E ;

Núñez, JI ;

Sobrino, F .

VIRUS RESEARCH, 2003, 91 (01) :47-63

[7] Prime-boost immunization using DNA vaccine and recombinant Orf virus protects pigs against Pseudorabies virus (Herpes suid 1) [J].

Dory, Daniel ;

Fischer, Timo ;

Beven, Veronique ;

Cariolet, Roland ;

Rziha, Hanns-Joachim ;

Jestin, Andre .

VACCINE, 2006, 24 (37-39) :6256-6263

[8] Coinfection by porcine circoviruses and porcine parvovirus in pigs with naturally acquired postweaning multisystemic wasting syndrome [J].

Ellis, JA ;

Bratanich, A ;

Clark, EG ;

Allan, G ;

Meehan, B ;

Haines, DM ;

Harding, J ;

West, KH ;

Krakowka, S ;

Konoby, C ;

Hassard, L ;

Martin, K ;

McNeilly, F .

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 2000, 12 (01) :21-27

[9] Construction and immunogenicity of recombinant pseudotype baculovirus expressing the capsid protein of porcine circovirus type 2 in mice [J].

Fan, Huiying ;

Pan, Yongfei ;

Fang, Liurong ;

Wang, Dang ;

Wang, Shengping ;

Jiang, Yunbo ;

Chen, Huanchun ;

Xiao, Shaobo .

JOURNAL OF VIROLOGICAL METHODS, 2008, 150 (1-2) :21-26

[10]

FRANCKI RIB, 1991, 5 INT COMM TAX VI S2, V2

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